IL-10RA Antikörper (N-Term)
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- Target Alle IL-10RA (IL10RA) Antikörper anzeigen
- IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Ratte, Rind (Kuh), Pferd, Hund, Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IL-10RA Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- GSVNLEIHNG FILGKIQLPR PKMAPANDTY ESIFSHFREY EIAIRKVPGN
- Homologie
- Cow: 77%, Dog: 92%, Guinea Pig: 92%, Horse: 85%, Human: 100%, Rat: 77%
- Produktmerkmale
- This is a rabbit polyclonal antibody against IL10RA. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human IL10RA
- Top Product
- Discover our top product IL10RA Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 578 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
- Andere Bezeichnung
- IL10RA (IL10RA Produkte)
- Synonyme
- IL10R1 antikoerper, IL10RA antikoerper, CD210 antikoerper, CD210a antikoerper, CDW210A antikoerper, HIL-10R antikoerper, IL-10R1 antikoerper, IL10R antikoerper, AW553859 antikoerper, CDw210 antikoerper, CDw210a antikoerper, Il10r antikoerper, mIL-10R antikoerper, interleukin 10 receptor subunit alpha antikoerper, interleukin 10 receptor, alpha antikoerper, IL10RA antikoerper, Il10ra antikoerper
- Hintergrund
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IL10RA is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases.The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases.
Alias Symbols: CDW210A, HIL-10R, IL-10R1, IL10R, CD210, CD210a
Protein Interaction Partner: BTRC, UBC, IL10RB, JAK1, IL10,
Protein Size: 578 - Molekulargewicht
- 61 kDa
- Gen-ID
- 3587
- NCBI Accession
- NM_001558, NP_001549
- UniProt
- Q13651
- Pathways
- Growth Factor Binding
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