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IL12RB2 Antikörper (Middle Region)
IL12RB2
Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Hund, Meerschweinchen, Pferd, Kaninchen, Schaf
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN2782132
Produktdetails anti-IL12RB2 Antikörper
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Target
Alle IL12RB2 Antikörper anzeigen
IL12RB2
(Interleukin 12 Receptor, beta 2 (IL12RB2))
Bindungsspezifität
Alle Epitope für IL12RB2 Antikörper
Middle Region
Reaktivität
Human, Maus, Ratte, Rind (Kuh), Schwein, Hund, Meerschweinchen, Pferd, Kaninchen, Schaf
Wirt
Alle Wirte für IL12RB2 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für IL12RB2 Antikörper
Polyklonal
Konjugat
Alle Konjugate für IL12RB2 Antikörper
Dieser IL12RB2 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für IL12RB2 Antikörper
Western Blotting (WB)
Sequenz
DVWYMKRHID YSRQQISLFW KNLSVSEARG KILHYQVTLQ ELTGGKAMTQ
Homologie
Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%, Sheep: 100%
Produktmerkmale
This is a rabbit polyclonal antibody against IL12RB2. It was validated on Western Blot.
Aufreinigung
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human IL12RB2
Top Product
Discover our top product IL12RB2 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeat freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Details zu IL12RB2
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Target
IL12RB2
(Interleukin 12 Receptor, beta 2 (IL12RB2))
Andere Bezeichnung
IL12RB2 (IL12RB2 Produkte )
Synonyme
IL12RB2 antikoerper, A930027I18Rik antikoerper, IL-12RB2 antikoerper, Ifnm antikoerper, interleukin 12 receptor subunit beta 2 antikoerper, interleukin 12 receptor, beta 2 antikoerper, IL12RB2 antikoerper, Il12rb2 antikoerper
Hintergrund
The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. Protein Interaction Partner: SOCS3, IL12RB2, IL12RB1, STAT4, IL12B, JAK2, Protein Size: 659
Molekulargewicht
72 kDa
Gen-ID
3595
Pathways
JAK-STAT Signalweg
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