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Indian Hedgehog Antikörper (N-Term)

IHH Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Rind (Kuh), Ziege, Pferd, Kaninchen, Zebrafisch (Danio rerio) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2782160
  • Target Alle Indian Hedgehog (IHH) Antikörper anzeigen
    Indian Hedgehog (IHH)
    Bindungsspezifität
    • 15
    • 10
    • 8
    • 8
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    Human, Maus, Ratte, Hund, Meerschweinchen, Rind (Kuh), Ziege, Pferd, Kaninchen, Zebrafisch (Danio rerio)
    Wirt
    • 69
    • 4
    • 4
    Kaninchen
    Klonalität
    • 69
    • 8
    Polyklonal
    Konjugat
    • 33
    • 8
    • 7
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Indian Hedgehog Antikörper ist unkonjugiert
    Applikation
    • 48
    • 37
    • 26
    • 13
    • 13
    • 9
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    AAWGCGPGRV VGSRRRPPRK LVPLAYKQFS PNVPEKTLGA SGRYEGKIAR
    Homologie
    Cow: 86%, Dog: 86%, Goat: 86%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
    Produktmerkmale
    This is a rabbit polyclonal antibody against IHH. It was validated on Western Blot and immunohistochemistry.
    Aufreinigung
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human IHH
    Top Product
    Discover our top product IHH Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 411 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Mirza, Qiao, Tateyama, Miyamoto, Xiuli, Seo: "3?-Hydroxysterol-Delta24 reductase plays an important role in long bone growth by protecting chondrocytes from reactive oxygen species." in: Journal of bone and mineral metabolism, Vol. 30, Issue 2, pp. 144-53, (2012) (PubMed).

  • Target
    Indian Hedgehog (IHH)
    Andere Bezeichnung
    IHH (IHH Produkte)
    Synonyme
    BDA1 antikoerper, HHG2 antikoerper, X-hh antikoerper, Xbhh antikoerper, bhh antikoerper, bhh-a antikoerper, IHH antikoerper, ehh antikoerper, zgc:113262 antikoerper, indian hedgehog antikoerper, Indian hedgehog antikoerper, indian hedgehog S homeolog antikoerper, Indian hedgehog homolog b antikoerper, IHH antikoerper, Ihh antikoerper, ihh.S antikoerper, ihhb antikoerper
    Hintergrund
    IHH is an intercellular signal essential for a variety of patterning events during development. It binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. It is implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones and induces the expression of parathyroid hormone-related protein (PTHRP).
    Alias Symbols: BDA1, HHG2
    Protein Interaction Partner: RHOD, HHIP, PTCH2, PTCH1,
    Protein Size: 411
    Molekulargewicht
    45 kDa
    Gen-ID
    3549
    NCBI Accession
    NM_002181, NP_002172
    UniProt
    Q14623
    Pathways
    Hedgehog Signalweg
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