Protocadherin 8 Antikörper (Middle Region)

Produktnummer ABIN2782185

Produktdetails anti-Protocadherin 8 Antikörper

Target: Protocadherin 8 (PCDH8)

Bindungsspezifität: Middle Region

Reaktivität: Human, Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Protocadherin 8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RVFRALLVIS DGGRPPLTTT ATVSFVVTAG GGRGPAAPAS AGSPERSRPP

Homologie: Dog: 92%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Rabbit: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against PCDH8. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PCDH8

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 973 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Protocadherin 8

Target: Protocadherin 8 (PCDH8)

Andere Bezeichnung: PCDH8 (PCDH8 Produkte)

Hintergrund: This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. PCDH8 is an integral membrane protein that is thought to function in cell adhesion in a CNS-specific manner. Unlike classical cadherins, which are generally encoded by 15-17 exons, this gene includes only 3 exons. Notable is the large first exon encoding the extracellular region, including 6 cadherin domains and a transmembrane region.This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes an integral membrane protein that is thought to function in cell adhesion in a CNS-specific manner. Unlike classical cadherins, which are generally encoded by 15-17 exons, this gene includes only 3 exons. Notable is the large first exon encoding the extracellular region, including 6 cadherin domains and a transmembrane region. Alternative splicing yields isoforms with unique cytoplasmic tails.
Alias Symbols: ARCADLIN, PAPC
Protein Interaction Partner: UBQLN4, BTRC, PCDH8,
Protein Size: 973

Molekulargewicht: 101 kDa

Gen-ID: 5100

NCBI Accession: NM_032949, NP_116567

UniProt: O95206