PIGA Antikörper (Middle Region)

Produktnummer ABIN2782188

Produktdetails anti-PIGA Antikörper

Target: PIGA (Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Kaninchen, Pferd, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIGA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: NHIICVSYTS KENTVLRAAL NPEIVSVIPN AVDPTDFTPD PFRRHDSITI

Homologie: Cow: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against PIGA. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PIGA

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 484 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PIGA

Target: PIGA (Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA))

Andere Bezeichnung: PIGA (PIGA Produkte)

Synonyme: GPI3 antikoerper, MCAHS2 antikoerper, PIG-A antikoerper, AI194334 antikoerper, Pig-a antikoerper, im:6911675 antikoerper, zgc:56589 antikoerper, phosphatidylinositol glycan anchor biosynthesis class A antikoerper, phosphatidylinositol glycan anchor biosynthesis, class A antikoerper, PIGA antikoerper, Piga antikoerper, piga antikoerper

Hintergrund: PIGA is a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the biosynthetic pathway of GPI anchor. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene.
Alias Symbols: GPI3, PIG-A
Protein Interaction Partner: UBC, ELAVL1, PIGY, DPM2, PIGQ, PIGH, PIGP,
Protein Size: 484

Molekulargewicht: 54 kDa

Gen-ID: 5277

NCBI Accession: NM_002641, NP_002632

UniProt: P37287

Pathways: Inositol Metabolic Process