SMPD2 Antikörper (N-Term)

Produktnummer ABIN2782209

Produktdetails anti-SMPD2 Antikörper

Target: SMPD2 (Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) (SMPD2))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Pferd, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMPD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RQKLSPTYPA AHHFRSGIIG SGLCVFSKHP IQELTQHIYT LNGYPYMIHH

Homologie: Cow: 79%, Dog: 86%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 77%, Rabbit: 79%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against SMPD2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SMPD2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 423 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SMPD2 Antikörper (ABIN2782209)

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Details zu SMPD2

Target: SMPD2 (Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) (SMPD2))

Andere Bezeichnung: SMPD2 (SMPD2 Produkte)

Hintergrund: SMPD2 converts sphingomyelin to ceramide. Hydrolyze 1-acyl-2-lyso-sn-glycero-3-phosphocholine (lyso-PC) and 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine (lyso-platelet-activating factor). The physiological substrate seems to be Lyso-PAF.
Alias Symbols: NSMASE, ISC1, NSMASE1
Protein Interaction Partner: UBC, PIK3CG,
Protein Size: 423

Molekulargewicht: 48 kDa

Gen-ID: 6610

NCBI Accession: NM_003080, NP_003071

UniProt: O60906

Pathways: Neurotrophin Signalübertragung