Transferrin Receptor 2 Antikörper (Middle Region)

Produktnummer ABIN2782222

Produktdetails anti-Transferrin Receptor 2 Antikörper

Target: Transferrin Receptor 2 (TFR2)

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Kaninchen, Rind (Kuh), Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Transferrin Receptor 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: YVSLDNAVLG DDKFHAKTSP LLTSLIESVL KQVDSPNHSG QTLYEQVVFT

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TFR2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TFR2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 801 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Transferrin Receptor 2

Target: Transferrin Receptor 2 (TFR2)

Andere Bezeichnung: TFR2 (TFR2 Produkte)

Synonyme: TFR2 antikoerper, Trfr2 antikoerper, HFE3 antikoerper, TFRC2 antikoerper, zgc:123043 antikoerper, transferrin receptor 2 antikoerper, TFR2 antikoerper, Tfr2 antikoerper, tfr2 antikoerper

Hintergrund: TFR2,a member of the transferrin receptor-like family,is a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III.This gene is a member of the transferrin receptor-like family and encodes a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HFE3, MGC126368, TFRC2
Protein Interaction Partner: FBXO6, ATP4A, SOCS3, UBC, HFE, TF,
Protein Size: 801

Molekulargewicht: 89 kDa

Gen-ID: 7036

NCBI Accession: NM_003227, NP_003218

UniProt: Q9UP52

Pathways: Transition Metal Ion Homeostasis