HNF4 gamma Antikörper (N-Term)

Produktnummer ABIN2782279

Produktdetails anti-HNF4 gamma Antikörper

Target: HNF4 gamma (HNF4G) (Hepatocyte Nuclear Factor 4 gamma (HNF4G))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HNF4 gamma Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MDMANYSEVL DPTYTTLEFE TMQILYNSSD SSAPETSMNT TDNGVNCLCA

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 86%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against HNF4G. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HNF4G

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 445 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-HNF4 gamma Antikörper (ABIN2782279)

Franke, Hampe, Rosenstiel, Becker, Wagner, Häsler, Little, Huse, Ruether, Balschun, Wittig, Elsharawy, Mayr, Albrecht, Prescott, Onnie, Fournier, Keith, Radelof, Platzer, Mathew, Stoll, Krawczak et al.: "Systematic association mapping identifies NELL1 as a novel IBD disease gene. ..." in: PLoS ONE, Vol. 2, Issue 8, pp. e691, (2007) (PubMed).

Details zu HNF4 gamma

Target: HNF4 gamma (HNF4G) (Hepatocyte Nuclear Factor 4 gamma (HNF4G))

Andere Bezeichnung: HNF4G (HNF4G Produkte)

Synonyme: HNF4G antikoerper, hnf4gamma antikoerper, zgc:153265 antikoerper, NR2A2 antikoerper, NR2A3 antikoerper, hepatocyte nuclear factor 4 gamma antikoerper, hepatocyte nuclear factor 4, gamma antikoerper, HNF4G antikoerper, hnf4g antikoerper, Hnf4g antikoerper

Hintergrund: HNF4 was first identified as a DNA binding activity in rat liver nuclear extracts and then was found to be an orphan member of the nuclear receptor superfamily. Binding sites for this factor were identified in many tissue-specifically expressed genes, and the protein was found to be essential for early embryonic development in the mouse
Alias Symbols: NR2A2, NR2A3
Protein Interaction Partner: NSD1, NCOA1, PNRC2, COPS5, PNRC1, HAX1, RANBP9, PRDX6, EIF3I, NR0B2, TNNI2, SRC, GAPDH, HLF,
Protein Size: 445

Molekulargewicht: 50 kDa

Gen-ID: 3174

NCBI Accession: NM_004133, NP_004124

UniProt: Q14541

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway