NR1I3 Antikörper (N-Term)
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- Target Alle NR1I3 Antikörper anzeigen
- NR1I3 (Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Hund, Meerschweinchen, Rind (Kuh), Schwein
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NR1I3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- MASREDELRN CVVCGDQATG YHFNALTCEG CKGFFRRTVS KSIGPTCPFA
- Homologie
- Cow: 90%, Dog: 92%, Guinea Pig: 79%, Human: 100%, Mouse: 92%, Pig: 100%, Rat: 92%
- Produktmerkmale
- This is a rabbit polyclonal antibody against NR1I3. It was validated on Western Blot and immunohistochemistry.
- Aufreinigung
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human NR1I3
- Top Product
- Discover our top product NR1I3 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 348 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- NR1I3 (Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3))
- Andere Bezeichnung
- NR1I3 (NR1I3 Produkte)
- Synonyme
- AA209988 antikoerper, AI551208 antikoerper, CAR antikoerper, CAR-beta antikoerper, Care2 antikoerper, ESTM32 antikoerper, MB67 antikoerper, CAR1 antikoerper, CXR antikoerper, nuclear receptor subfamily 1 group I member 3 antikoerper, nuclear receptor subfamily 1, group I, member 3 antikoerper, NR1I3 antikoerper, Nr1i3 antikoerper
- Hintergrund
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NR1I3 mediates the induction of transcription of cytochrome P450 (CYP) genes by phenobarbital (PB) and PB-type inducers. NR1I3 activation induces hepatic expression of detoxification enzymes and transporters and increases liver size. NR1I3 can also regulate both liver homeostasis and tumorigenesis in response to xenobiotic stresses.
Alias Symbols: CAR, CAR1, MB67, MGC150433, MGC97144, MGC97209
Protein Interaction Partner: HSP90AA1, RXRA, CHD9, SNX13, SNRPD3, IGH, PSMC5, PSMC4, EIF3I, SRC, MAP4, FTH1, HNF4A, NR0B2, PPARGC1A, MED1, NCOA1, POU1F1,
Protein Size: 348 - Molekulargewicht
- 39 kDa
- Gen-ID
- 9970
- NCBI Accession
- NM_005122, NP_005113
- UniProt
- Q5VTW5
- Pathways
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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