MBL2 Antikörper (Middle Region)

Produktnummer ABIN2782311

Produktdetails anti-MBL2 Antikörper

Target: MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Rind (Kuh), Ziege, Schaf, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MBL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KEEAFLGITD EKTEGQFVDL TGNRLTYTNW NEGEPNNAGS DEDCVLLLKN

Homologie: Cow: 77%, Goat: 77%, Horse: 92%, Human: 100%, Pig: 92%, Rat: 77%, Sheep: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against MBL2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MBL2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 248 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MBL2

Target: MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))

Andere Bezeichnung: MBL2 (MBL2 Produkte)

Hintergrund: This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases.
Alias Symbols: COLEC1, HSMBPC, MBL, MBP, MBP1, MGC116832, MGC116833, MBL2D, MBP-C
Protein Interaction Partner: MASP2, MAD2L1, MASP1, MBL2, PTPRC, KRT1, CD93, CALCR, CALR,
Protein Size: 248

Molekulargewicht: 24 kDa

Gen-ID: 4153

NCBI Accession: NM_000242, NP_000233

UniProt: Q66S64

Pathways: Komplementsystem, Positive Regulation of Immune Effector Process