PFKL Antikörper (Middle Region)

Produktnummer ABIN2782359

Produktdetails anti-PFKL Antikörper

Target: PFKL (Phosphofructokinase, Liver (PFKL))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Schaf, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PFKL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RTNVLGHLQQ GGAPTPFDRN YGTKLGVKAM LWLSEKLREV YRKGRVFANA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 79%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against PFKL. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PFKL

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 568 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PFKL Antikörper (ABIN2782359)

Spellman, Ahmed, Dubach, Gardiner: "Expression of trisomic proteins in Down syndrome model systems." in: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).

Details zu PFKL

Target: PFKL (Phosphofructokinase, Liver (PFKL))

Andere Bezeichnung: PFKL (PFKL Produkte)

Hintergrund: Phosphofructokinase (PFK) is a tetrameric enzyme that catalyzes a key step in glycolysis, namely the conversion of D-fructose 6-phosphate to D-fructose 1,6-bisphosphate. PFK from muscle is a homotetramer of M subunit, PFK from liver is a homotetramer of L-subunits, while PFK from platelets can be composed of any tetrameric combination of M and L subunits. PFKL represents the L subunit.
Alias Symbols: DKFZp686G1648, DKFZp686L2097, FLJ30173, FLJ40909, PFK-B
Protein Interaction Partner: KRTAP10-7, GTPBP3, PFKL, KRTAP5-9, FUS, STAU1, UBC, EGFR, RNF2, rev, ZC3HC1, PSMD9, FBXO6, YWHAQ, HDAC6, PRPF40A, TESK1, PFKM, MYD88, ITGA4, FN1, PCBP3, PRDX3, PFKP, APP, ATN1, RAD21, SNW1, TERF2, ATG101, TAF13, TAF10, DMWD, COPS6, KRTAP4-12,
Protein Size: 568

Molekulargewicht: 64 kDa

Gen-ID: 5211

NCBI Accession: NM_002626

UniProt: P17858

Pathways: Negative Regulation of Hormone Secretion, Warburg Effekt