C21orf33 Antikörper (N-Term)
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- Target Alle C21orf33 Antikörper anzeigen
- C21orf33 (Chromosome 21 Open Reading Frame 33 (C21orf33))
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Bindungsspezifität
- N-Term
- Reaktivität
- Human, Ratte, Maus, Rind (Kuh), Meerschweinchen, Pferd, Schaf, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser C21orf33 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- SRGGAEVQIF APDVPQMHVI DHTKGQPSEG ESRNVLTESA RIARGKITDL
- Homologie
- Cow: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 92%, Rat: 100%, Sheep: 93%, Zebrafish: 86%
- Produktmerkmale
- This is a rabbit polyclonal antibody against C21orf33. It was validated on Western Blot and immunohistochemistry.
- Aufreinigung
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human C21orf33
- Top Product
- Discover our top product C21orf33 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 237 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- C21orf33 (Chromosome 21 Open Reading Frame 33 (C21orf33))
- Andere Bezeichnung
- C21orf33 (C21orf33 Produkte)
- Synonyme
- C21orf33 antikoerper, es1 antikoerper, knph antikoerper, knpi antikoerper, ES1 antikoerper, GT335 antikoerper, HES1 antikoerper, KNPH antikoerper, KNPI antikoerper, chromosome 21 open reading frame, human C21orf33 antikoerper, chromosome 1 open reading frame, human C21orf33 antikoerper, chromosome 3 open reading frame, human C21orf33 antikoerper, chromosome 21 open reading frame 33 antikoerper, chromosome 21 open reading frame 33 L homeolog antikoerper, DNA segment, Chr 10, Johns Hopkins University 81 expressed antikoerper, homolog of zebrafish ES1 antikoerper, C21H21orf33 antikoerper, C1H21ORF33 antikoerper, C3H21orf33 antikoerper, c21orf33 antikoerper, C1H21orf33 antikoerper, c21orf33.L antikoerper, C21orf33 antikoerper, D10Jhu81e antikoerper, RGD1303003 antikoerper
- Hintergrund
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C21orf33 inhibits both estrogen- and heregulin-beta1-stimulated growth of breast cancer cells, and further suggests that growth inhibition induced in these cells by all-trans retinoic acid occurs via HES-1-mediated downregulation of E2F-1 expression. C21orf33 may also be a candidate protein involved in the pathogenesis of the brain deficit in DS.
Alias Symbols: D21S2048E, ES1, GT335, HES1, KNP-I, KNPH, KNPI
Protein Interaction Partner: UBC, SUMO1, NEDD8, APP, FRA10AC1,
Protein Size: 237 - Molekulargewicht
- 21 kDa
- Gen-ID
- 8209
- NCBI Accession
- NM_198155, NP_937798
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