C21orf33 Antikörper (N-Term)

Produktnummer ABIN310734

Produktdetails anti-C21orf33 Antikörper

Target: C21orf33 (Chromosome 21 Open Reading Frame 33 (C21orf33))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Schaf, Zebrafisch (Danio rerio), Rind (Kuh), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C21orf33 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: SRGGAEVQIF APDVPQMHVI DHTKGQPSEG ESRNVLTESA RIARGKITDL

Homologie: Cow: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 92%, Rat: 100%, Sheep: 93%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against C21orf33. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human C21orf33

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 237 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu C21orf33

Target: C21orf33 (Chromosome 21 Open Reading Frame 33 (C21orf33))

Andere Bezeichnung: C21orf33 (C21orf33 Produkte)

Hintergrund: C21orf33 inhibits both estrogen- and heregulin-beta1-stimulated growth of breast cancer cells, and further suggests that growth inhibition induced in these cells by all-trans retinoic acid occurs via HES-1-mediated downregulation of E2F-1 expression. C21orf33 may also be a candidate protein involved in the pathogenesis of the brain deficit in DS.
Alias Symbols: D21S2048E, ES1, GT335, HES1, KNP-I, KNPH, KNPI
Protein Interaction Partner: UBC, SUMO1, NEDD8, APP, FRA10AC1,
Protein Size: 237

Molekulargewicht: 21 kDa

Gen-ID: 8209

NCBI Accession: NM_198155, NP_937798