CHAF1B Antikörper (N-Term)

Produktnummer ABIN2782376

Produktdetails anti-CHAF1B Antikörper

Target: CHAF1B (Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Schwein, Kaninchen, Rind (Kuh), Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHAF1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KVITCEIAWH NKEPVYSLDF QHGTAGRIHR LASAGVDTNV RIWKVEKGPD

Homologie: Cow: 92%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against CHAF1B. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CHAF1B

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 559 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CHAF1B Antikörper (ABIN2782376)

Spellman, Ahmed, Dubach, Gardiner: "Expression of trisomic proteins in Down syndrome model systems." in: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).

Details zu CHAF1B

Target: CHAF1B (Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B))

Andere Bezeichnung: CHAF1B (CHAF1B Produkte)

Synonyme: CHAF1B antikoerper, wu:fd07c09 antikoerper, wu:fe36g06 antikoerper, wu:fv38g09 antikoerper, zgc:56096 antikoerper, CAF-1 antikoerper, CAF-IP60 antikoerper, CAF1 antikoerper, CAF1A antikoerper, CAF1P60 antikoerper, MPHOSPH7 antikoerper, MPP7 antikoerper, 2600017H24Rik antikoerper, C76145 antikoerper, CAF-I p60 antikoerper, CAF-Ip60 antikoerper, caf-1 antikoerper, CAF-1P60 antikoerper, chromatin assembly factor 1 subunit B antikoerper, chromatin assembly factor 1, subunit B antikoerper, chromatin assembly factor 1, subunit B (p60) antikoerper, chromatin assembly factor 1 subunit B L homeolog antikoerper, CHAF1B antikoerper, chaf1b antikoerper, Chaf1b antikoerper, chaf1b.L antikoerper

Hintergrund: Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. CHAF1B corresponds to the p60 subunit and is required for chromatin assembly after replication. CHAF1B is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair. Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CAF-1, CAF-IP60, CAF1, CAF1A, CAF1P60, MPHOSPH7, MPP7
Protein Interaction Partner: UBC, SOX2, CNOT6L, env, CBX6, CBX5, HIST1H3B, HIST1H3A, CHAF1A, PCNA, APP, HIST2H3C, HIST1H4F, HIST1H3E, HIST3H3, SUMO2, BANF1, ASF1B, ASF1A, SETDB1, RBBP4, CDK2, CDK1,
Protein Size: 559

Molekulargewicht: 61 kDa

Gen-ID: 8208

NCBI Accession: NM_005441, NP_005432

UniProt: Q13112