SIK1 Antikörper (N-Term)

Produktnummer ABIN2782413

Produktdetails anti-SIK1 Antikörper

Target: SIK1 (Salt-Inducible Kinase 1 (SIK1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Pferd, Hund, Meerschweinchen, Rind (Kuh), Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: MVIMSEFSAD PAGQGQGQQK PLRVGFYDIE RTLGKGNFAV VKLARHRVTK

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 90%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SNF1LK. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SNF1LK

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 783 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SIK1

Target: SIK1 (Salt-Inducible Kinase 1 (SIK1))

Andere Bezeichnung: SNF1LK (SIK1 Produkte)

Synonyme: Msk antikoerper, Sik antikoerper, Snf1lk antikoerper, SIK2 antikoerper, SNF1LK antikoerper, MSK antikoerper, SIK antikoerper, salt-inducible kinase 1 antikoerper, salt inducible kinase 1 antikoerper, SIK1 antikoerper, Sik1 antikoerper

Hintergrund: SNF1LK play a transient role during the earliest stages of myocardial cell differentiation and/or primitive chamber formation and may also be important for the earliest stages of skeletal muscle growth and/or differentiation. It also plays a potential role in G2/M cell cycle regulation. It inhibits CREB activity by phosphorylating and repressing the CREB-specific coactivators, CRTC1-3.
Alias Symbols: MSK, SIK, SNF1LK
Protein Interaction Partner: TAB2, MAP3K7, HDAC5, UBC, SUPT5H, RPL3, PRKACA, NMNAT1, STK11, ELAVL1, YWHAZ, PRKAA1, CRTC2, VAPA,
Protein Size: 783

Molekulargewicht: 85 kDa

Gen-ID: 150094

NCBI Accession: NM_173354, NP_775490

UniProt: P57059

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process