GM2A Antikörper (N-Term)

Produktnummer ABIN2782426

Produktdetails anti-GM2A Antikörper

Target: GM2A (GM2 Ganglioside Activator (GM2A))

Bindungsspezifität: N-Term

Reaktivität: Human, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GM2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SWDNCDEGKD PAVIRSLTLE PDPIIVPGNV TLSVMGSTSV PLSSPLKVDL

Homologie: Guinea Pig: 83%, Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against GM2A. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GM2A

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 193 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GM2A

Target: GM2A (GM2 Ganglioside Activator (GM2A))

Andere Bezeichnung: GM2A (GM2A Produkte)

Synonyme: GM2A antikoerper, fb96e04 antikoerper, fb96e10 antikoerper, wu:fb96e04 antikoerper, wu:fb96e10 antikoerper, zgc:110188 antikoerper, MGC84154 antikoerper, GM2-AP antikoerper, SAP-3 antikoerper, AA408702 antikoerper, AW215435 antikoerper, GM2 ganglioside activator antikoerper, GM2 ganglioside activator L homeolog antikoerper, GM2 ganglioside activator protein antikoerper, Gm2a antikoerper, GM2A antikoerper, gm2a antikoerper, gm2a.L antikoerper

Hintergrund: This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants.
Alias Symbols: SAP-3, GM2-AP
Protein Interaction Partner: ELAVL1, UBC, HEXA, GPLD1, PLD2,
Protein Size: 193

Molekulargewicht: 21 kDa

Gen-ID: 2760

NCBI Accession: NM_000405, NP_000396

UniProt: P17900