RRM2 Antikörper (N-Term)
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- Target Alle RRM2 Antikörper anzeigen
- RRM2 (Ribonucleotide Reductase M2 (RRM2))
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Bindungsspezifität
- N-Term
- Reaktivität
- Human, Ratte, Meerschweinchen, Pferd, Rind (Kuh), Hund
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RRM2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- PALSGTRVLA SKTARRIFQE PTEPKTKAAA PGVEDEPLLR ENPRRFVIFP
- Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Rat: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against RRM2. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human RRM2
- Top Product
- Discover our top product RRM2 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 389 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Cell cycle-regulated protein abundance changes in synchronously proliferating HeLa cells include regulation of pre-mRNA splicing proteins." in: PLoS ONE, Vol. 8, Issue 3, pp. e58456, (2013) (PubMed).
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Cell cycle-regulated protein abundance changes in synchronously proliferating HeLa cells include regulation of pre-mRNA splicing proteins." in: PLoS ONE, Vol. 8, Issue 3, pp. e58456, (2013) (PubMed).
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- Target
- RRM2 (Ribonucleotide Reductase M2 (RRM2))
- Andere Bezeichnung
- RRM2 (RRM2 Produkte)
- Synonyme
- R2 antikoerper, RR2 antikoerper, RR2M antikoerper, AA407299 antikoerper, rrm2 antikoerper, rr2m antikoerper, cb111 antikoerper, chunp6884 antikoerper, r2 antikoerper, ribonucleotide reductase regulatory subunit M2 antikoerper, ribonucleotide reductase M2 antikoerper, ribonucleotide reductase M2, gene 2 L homeolog antikoerper, ribonucleotide reductase M2, gene 1 antikoerper, ribonucleotide reductase M2 polypeptide antikoerper, RRM2 antikoerper, Rrm2 antikoerper, rrm2.2.L antikoerper, rrm2.1 antikoerper, rrm2 antikoerper
- Hintergrund
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RRM2 provides the precursors necessary for DNA synthesis. RRM2 catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. RRM2 inhibits Wnt signaling.Ribonucleotide reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. It is composed of 2 non-identical subunits, proteins M1 and M2. Synthesis of M2 is regulated in a cell-cycle dependent fashion. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: R2, RR2M, RR2
Protein Interaction Partner: DNM1L, UBC, gag-pol, RBMX, PCMT1, NONO, UBD, SKP2, NR1H4, RRM1, CCNF, ELAVL1, KAT5, RRM2B, CDH1, TP53, CDK1,
Protein Size: 389 - Molekulargewicht
- 45 kDa
- Gen-ID
- 6241
- NCBI Accession
- NM_001034, NP_001025
- UniProt
- P31350
- Pathways
- Mitotic G1-G1/S Phases
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