CRYZ Antikörper (Middle Region)

Produktnummer ABIN2782462

Produktdetails anti-CRYZ Antikörper

Target: CRYZ (Crystallin, zeta (CRYZ))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd, Schwein, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRYZ Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KGIDIIIEML ANVNLSKDLS LLSHGGRVIV VGSRGTIEIN PRDTMAKESS

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 85%, Rat: 86%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against CRYZ. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CRYZ

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 329 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CRYZ

Target: CRYZ (Crystallin, zeta (CRYZ))

Andere Bezeichnung: CRYZ (CRYZ Produkte)

Hintergrund: Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. CRYZ is a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low.Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. This gene encodes a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low. One pseudogene is known to exist.
Alias Symbols: DKFZp779E0834, FLJ41475
Protein Interaction Partner: UBC, TXNRD1, TUBA4A, SPTAN1, PFKP, KRT17, GAPDH, TUBB, IGF2BP3, BASP1, CRYAA,
Protein Size: 329

Molekulargewicht: 35 kDa

Gen-ID: 1429

NCBI Accession: NM_001889, NP_001880

UniProt: Q08257