CTH Antikörper (N-Term)
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- Target Alle CTH Antikörper anzeigen
- CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen, Pferd, Schwein
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CTH Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- VPPISLSTTF KQGAPGQHSG FEYSRSGNPT RNCLEKAVAA LDGAKYCLAF
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 92%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against CTH. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human CTH
- Top Product
- Discover our top product CTH Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 405 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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An emerging role for gasotransmitters in the control of breathing and ionic regulation in fish." in: Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, Vol. 186, Issue 2, pp. 145-59, (2016) (PubMed).
: "Hydrogen sulfide inhibits Na+ uptake in larval zebrafish, Danio rerio." in: Pflügers Archiv : European journal of physiology, Vol. 467, Issue 4, pp. 651-64, (2015) (PubMed).
: "The role of hydrogen sulphide in the control of breathing in hypoxic zebrafish (Danio rerio)." in: The Journal of physiology, Vol. 592, Issue 14, pp. 3075-88, (2014) (PubMed).
: "
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An emerging role for gasotransmitters in the control of breathing and ionic regulation in fish." in: Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, Vol. 186, Issue 2, pp. 145-59, (2016) (PubMed).
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- Target
- CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))
- Andere Bezeichnung
- CTH (CTH Produkte)
- Hintergrund
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CTH is a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in its gene cause cystathioninuria.This gene encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Alias Symbols: MGC9471
Protein Interaction Partner: GUCD1, WDYHV1, RECK, CTH, PTMA, GMDS, CAPN2, ATIC, SDCBP2, UBC, ELAVL1,
Protein Size: 405 - Molekulargewicht
- 44 kDa
- Gen-ID
- 1491
- NCBI Accession
- NM_001902, NP_001893
- UniProt
- P32929
- Pathways
- ER-Nucleus Signaling, Warburg Effekt
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