CTH Antikörper (N-Term)

Produktnummer ABIN2782463

Produktdetails anti-CTH Antikörper

Target: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CTH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VPPISLSTTF KQGAPGQHSG FEYSRSGNPT RNCLEKAVAA LDGAKYCLAF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 92%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CTH. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CTH

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 405 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CTH Antikörper (ABIN2782463)

Perry, Kumai, Porteus, Tzaneva, Kwong: "An emerging role for gasotransmitters in the control of breathing and ionic regulation in fish." in: Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, Vol. 186, Issue 2, pp. 145-59, (2016) (PubMed).

Kumai, Porteus, Kwong, Perry: "Hydrogen sulfide inhibits Na+ uptake in larval zebrafish, Danio rerio." in: Pflügers Archiv : European journal of physiology, Vol. 467, Issue 4, pp. 651-64, (2015) (PubMed).

Porteus, Abdallah, Pollack, Kumai, Kwong, Yew, Milsom, Perry: "The role of hydrogen sulphide in the control of breathing in hypoxic zebrafish (Danio rerio)." in: The Journal of physiology, Vol. 592, Issue 14, pp. 3075-88, (2014) (PubMed).

Details zu CTH

Target: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Andere Bezeichnung: CTH (CTH Produkte)

Synonyme: DYT17 antikoerper, DYT18 antikoerper, DYT9 antikoerper, EIG12 antikoerper, GLUT antikoerper, GLUT1 antikoerper, GLUT1DS antikoerper, HTLVR antikoerper, PED antikoerper, wu:fb48e03 antikoerper, wu:fb58d08 antikoerper, zgc:66001 antikoerper, zgc:85785 antikoerper, CTH antikoerper, 0610010I13Rik antikoerper, AI314617 antikoerper, BC019483 antikoerper, CSE antikoerper, Cys3 antikoerper, cysA antikoerper, SCQ11.03c antikoerper, DDBDRAFT_0190313 antikoerper, DDBDRAFT_0191318 antikoerper, DDB_0190313 antikoerper, DDB_0191318 antikoerper, H antikoerper, MGC75946 antikoerper, cystathionine gamma-lyase antikoerper, solute carrier family 2 member 1 antikoerper, cystathionase (cystathionine gamma-lyase) antikoerper, cystathionine gamma-lyase L homeolog antikoerper, CTH antikoerper, SLC2A1 antikoerper, cth antikoerper, Cth antikoerper, SCO3920 antikoerper, mlr1566 antikoerper, TA_RS00415 antikoerper, MAP_RS15640 antikoerper, SPO3344 antikoerper, CNN01730 antikoerper, Mmcs_1928 antikoerper, RHA1_RS31820 antikoerper, HNE_1212 antikoerper, MAV_3867 antikoerper, MSMEG_2394 antikoerper, Mvan_2142 antikoerper, SACE_6136 antikoerper, Mflv_4220 antikoerper, cysA antikoerper, cth.L antikoerper

Hintergrund: CTH is a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in its gene cause cystathioninuria.This gene encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Alias Symbols: MGC9471
Protein Interaction Partner: GUCD1, WDYHV1, RECK, CTH, PTMA, GMDS, CAPN2, ATIC, SDCBP2, UBC, ELAVL1,
Protein Size: 405

Molekulargewicht: 44 kDa

Gen-ID: 1491

NCBI Accession: NM_001902, NP_001893

UniProt: P32929

Pathways: ER-Nucleus Signaling, Warburg Effekt