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CTH Antikörper (N-Term)

CTH Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen, Pferd, Schwein WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2782463
  • Target Alle CTH Antikörper anzeigen
    CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))
    Bindungsspezifität
    • 13
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 56
    • 33
    • 32
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen, Pferd, Schwein
    Wirt
    • 50
    • 10
    Kaninchen
    Klonalität
    • 50
    • 10
    Polyklonal
    Konjugat
    • 31
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CTH Antikörper ist unkonjugiert
    Applikation
    • 44
    • 16
    • 13
    • 11
    • 9
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB)
    Sequenz
    VPPISLSTTF KQGAPGQHSG FEYSRSGNPT RNCLEKAVAA LDGAKYCLAF
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 92%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against CTH. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human CTH
    Top Product
    Discover our top product CTH Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 405 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Perry, Kumai, Porteus, Tzaneva, Kwong: "An emerging role for gasotransmitters in the control of breathing and ionic regulation in fish." in: Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, Vol. 186, Issue 2, pp. 145-59, (2016) (PubMed).

    Kumai, Porteus, Kwong, Perry: "Hydrogen sulfide inhibits Na+ uptake in larval zebrafish, Danio rerio." in: Pflügers Archiv : European journal of physiology, Vol. 467, Issue 4, pp. 651-64, (2015) (PubMed).

    Porteus, Abdallah, Pollack, Kumai, Kwong, Yew, Milsom, Perry: "The role of hydrogen sulphide in the control of breathing in hypoxic zebrafish (Danio rerio)." in: The Journal of physiology, Vol. 592, Issue 14, pp. 3075-88, (2014) (PubMed).

  • Target
    CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))
    Andere Bezeichnung
    CTH (CTH Produkte)
    Hintergrund
    CTH is a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in its gene cause cystathioninuria.This gene encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
    Alias Symbols: MGC9471
    Protein Interaction Partner: GUCD1, WDYHV1, RECK, CTH, PTMA, GMDS, CAPN2, ATIC, SDCBP2, UBC, ELAVL1,
    Protein Size: 405
    Molekulargewicht
    44 kDa
    Gen-ID
    1491
    NCBI Accession
    NM_001902, NP_001893
    UniProt
    P32929
    Pathways
    ER-Nucleus Signaling, Warburg Effekt
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