MAGEA6 Antikörper (Middle Region)

Produktnummer ABIN2782499

Produktdetails anti-MAGEA6 Antikörper

Target: MAGEA6 (Melanoma Antigen Family A, 6 (MAGEA6))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Schwein, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAGEA6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: APEEKIWEEL SVLEVFEGRE DSIFGDPKKL LTQYFVQENY LEYRQVPGSD

Homologie: Dog: 83%, Horse: 83%, Human: 100%, Mouse: 83%, Pig: 83%, Rabbit: 83%, Rat: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against MAGEA6. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MAGEA6

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 314 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MAGEA6

Target: MAGEA6 (Melanoma Antigen Family A, 6 (MAGEA6))

Andere Bezeichnung: MAGEA6 (MAGEA6 Produkte)

Synonyme: Mage-a6 antikoerper, CT1.6 antikoerper, MAGE-3b antikoerper, MAGE3B antikoerper, MAGE6 antikoerper, melanoma antigen, family A, 6 antikoerper, MAGE family member A6 antikoerper, Magea6 antikoerper, MAGEA6 antikoerper

Hintergrund: MAGEA6 gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Two transcript variants encoding the same protein have been identified for this gene.
Alias Symbols: MAGE-3b, MAGE3B, MAGE6, MGC52297, CT1.6
Protein Interaction Partner: KLHL38, MORN3, LCORL, IQUB, MIPOL1, ANKRD26P1, SNAP47, HAUS1, ATPAF2, ELMOD3, RASSF4, SH2D4A, LSM2, CCDC146, STAMBPL1, S100A14, FAM214A, LIN37, RCOR3, GFOD1, FRMPD1, ACOT7, EXOC5, BET1, TXNDC9, AKAP9, ATP6V1G1, BCL7B, SNX4, NCK2, TULP3, STX5, RPL37A, PDE4
Protein Size: 314

Molekulargewicht: 35 kDa

Gen-ID: 4105

NCBI Accession: NM_005363, NP_005354

UniProt: P43360