SMC4 Antikörper (N-Term)

Produktnummer ABIN502709

Produktdetails anti-SMC4 Antikörper

Target: SMC4 (Structural Maintenance of Chromosomes 4 (SMC4))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Hund, Pferd, Rind (Kuh), Kaninchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMC4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SGRTESPATA AETASEELDN RSLEEILNSI PPPPPPAMTN EAGAPRLMIT

Homologie: Cow: 86%, Dog: 86%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 86%, Rabbit: 93%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against SMC4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SMC4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1288 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SMC4

Target: SMC4 (Structural Maintenance of Chromosomes 4 (SMC4))

Andere Bezeichnung: SMC4 (SMC4 Produkte)

Hintergrund: SMC4 is the central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Alias Symbols: CAPC, SMC4L1, hCAP-C, CAP-C, SMC-4
Protein Interaction Partner: UBC, SUMO2, LGR4, RPA3, RPA2, RPA1, RNF2, NCAPH, SMC2, SSSCA1, NCAPD2, TBC1D4, PLEC, AP3S1, CDK9, NCAPG, CCAR2, RABL6, TOPBP1, FBXO6, UBD, HDAC11, MYC, Nfe2l2, NEDD8, CDK2, SIRT7, NCAPH2, NCAPD3, RAD21, TRAF3IP1, SUMO1, HDAC1, tat, DNMT3B,
Protein Size: 1288

Molekulargewicht: 147 kDa

Gen-ID: 10051

NCBI Accession: NM_001002800, NP_001002800

UniProt: Q9NTJ3