PPIF Antikörper (Middle Region)

Produktnummer ABIN2782510

Produktdetails anti-PPIF Antikörper

Target: PPIF (Peptidylprolyl Isomerase F (PPIF))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus, Kaninchen, Hund, Rind (Kuh), Meerschweinchen, Pferd, Saccharomyces cerevisiae, Schaf, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPIF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GSTFHRVIPS FMCQAGDFTN HNGTGGKSIY GSRFPDENFT LKHVGPGVLS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 92%, Yeast: 100%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against PPIF. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PPIF

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 207 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PPIF

Target: PPIF (Peptidylprolyl Isomerase F (PPIF))

Andere Bezeichnung: PPIF (PPIF Produkte)

Hintergrund: PPIF is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.
Alias Symbols: CYP3, Cyp-D, FLJ90798, MGC117207
Protein Interaction Partner: CMTM5, BANP, ABI2, MDM2, UBC, ATF2, MPLKIP, MRPL53, MRRF, NDUFAF2, SLIRP, NABP2, MRPL14, SRPRB, SUGP1, TPX2, TIMM44, UBE4B, ZC3H11A, STX7, VDAC3, RRBP1, RBMS1, RANGAP1, PTPN11, ATP6V1E1, VDAC1, SLC25A4,
Protein Size: 207

Molekulargewicht: 19 kDa

Gen-ID: 10105

NCBI Accession: NM_005729, NP_005720

UniProt: P30405

Pathways: Proton Transport, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity