MRPL15 Antikörper (N-Term)

Produktnummer ABIN2782532

Produktdetails anti-MRPL15 Antikörper

Target: MRPL15 (Mitochondrial Ribosomal Protein L15 (MRPL15))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Zebrafisch (Danio rerio), Rind (Kuh), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MRPL15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KPERRPRGRR RGRKCGRGHK GERQRGTRPR LGFEGGQTPF YIRIPKYGFN

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MRPL15. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MRPL15

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 296 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-MRPL15 Antikörper (ABIN2782532)

Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).

Details zu MRPL15

Target: MRPL15 (Mitochondrial Ribosomal Protein L15 (MRPL15))

Andere Bezeichnung: MRPL15 (MRPL15 Produkte)

Synonyme: L15mt antikoerper, MRP-L15 antikoerper, MRP-L7 antikoerper, RPML7 antikoerper, HSPC145 antikoerper, Rpml7 antikoerper, zgc:92856 antikoerper, mitochondrial ribosomal protein L15 antikoerper, mitochondrial ribosomal protein L15 L homeolog antikoerper, MRPL15 antikoerper, Mrpl15 antikoerper, mrpl15 antikoerper, mrpl15.L antikoerper

Hintergrund: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. MRPL15 belongs to the ribosomal protein L15P family. It is a 39S subunit protein that belongs to the EcoL15 ribosomal protein family. Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL15 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 15q.
Alias Symbols: HSPC145, MRP-L7, RPML7, L15mt, MRP-L15
Protein Interaction Partner: CCNDBP1, RUNDC3A, UBC, SOX2, MRPL55, MRPL10, MRPL45, TMEM177, MRPL57, MRPL9, MRPL11, MRPL32, MRPL38, MRPL40, MRPL14, MARC1, NDUFA12, MRPL16, MRPL50, MRPL39, MRPL4, MRPL13, FKBP8, SCFD1, MRPL19, EIF3C, MRPL12, OGDH, NDUFS4, ILF3, DLST, CYC1, COX15, CAND1,
Protein Size: 296

Molekulargewicht: 33 kDa

Gen-ID: 29088

NCBI Accession: NM_014175, NP_054894

UniProt: Q9P015