PDSS1 Antikörper (Middle Region)

Produktnummer ABIN2782534

Produktdetails anti-PDSS1 Antikörper

Target: PDSS1 (Prenyl (Decaprenyl) Diphosphate Synthase, Subunit 1 (PDSS1))

Bindungsspezifität: Middle Region

Reaktivität: Maus, Human, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Ratte, Pferd, Schwein, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDSS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GEFLQLGSKE NENERFAHYL EKTFKKTASL IANSCKAVSV LGCPDPVVHE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against PDSS1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PDSS1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 415 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PDSS1

Target: PDSS1 (Prenyl (Decaprenyl) Diphosphate Synthase, Subunit 1 (PDSS1))

Andere Bezeichnung: PDSS1 (PDSS1 Produkte)

Synonyme: COQ1 antikoerper, COQ10D2 antikoerper, DPS antikoerper, RP13-16H11.3 antikoerper, SPS antikoerper, TPRT antikoerper, TPT antikoerper, TPT 1 antikoerper, hDPS1 antikoerper, 2610203G20Rik antikoerper, 2700031G06Rik antikoerper, Tprt antikoerper, mDLP1 antikoerper, mSPS1 antikoerper, tprt antikoerper, wu:fc11f12 antikoerper, wu:fd05d05 antikoerper, zgc:112058 antikoerper, T30F21.15 antikoerper, T30F21_15 antikoerper, solanesyl diphosphate synthase 1 antikoerper, decaprenyl diphosphate synthase subunit 1 antikoerper, prenyl (solanesyl) diphosphate synthase, subunit 1 antikoerper, prenyl (decaprenyl) diphosphate synthase, subunit 1 antikoerper, solanesyl diphosphate synthase 1 antikoerper, PDSS1 antikoerper, Pdss1 antikoerper, pdss1 antikoerper, SPS1 antikoerper

Hintergrund: PDSS1 is an enzyme that elongates the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. PDSS1 catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. The protein may be peripherally associated with the inner mitochondrial membrane, though no transit peptide has been definitively identified to date. Defects in PDSS1 gene are a cause of coenzyme Q10 deficiency.The protein encoded by this gene is an enzyme that elongates the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. The protein may be peripherally associated with the inner mitochondrial membrane, though no transit peptide has been definitively identified to date. Defects in this gene are a cause of coenzyme Q10 deficiency.
Alias Symbols: COQ1, MGC70953, RP13-16H11.3, TPRT, TPT, hDPS1, DPS, SPS, TPT 1
Protein Interaction Partner: UBC,
Protein Size: 415

Molekulargewicht: 46 kDa

Gen-ID: 23590

NCBI Accession: NM_014317, NP_055132

UniProt: Q5T2R2