SWAP70 Antikörper (N-Term)

Produktnummer ABIN2782542

Produktdetails anti-SWAP70 Antikörper

Target: SWAP70 (SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SWAP70 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ALEEHFRDDD EGPVSNQGYM PYLNRFILEK VQDNFDKIEF NRMCWTLCVK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SWAP70. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SWAP70

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 585 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SWAP70 Antikörper (ABIN2782542)

Rosati, Krebs, Liu: "Emissions from cooking microwave popcorn." in: Critical reviews in food science and nutrition, Vol. 47, Issue 8, pp. 701-9, (2007) (PubMed).

Details zu SWAP70

Target: SWAP70 (SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))

Andere Bezeichnung: SWAP70 (SWAP70 Produkte)

Synonyme: SWAP-70 antikoerper, 70kDa antikoerper, AV235546 antikoerper, HSPC321 antikoerper, swap70b antikoerper, zgc:63599 antikoerper, switching B-cell complex subunit SWAP70 antikoerper, SWA-70 protein antikoerper, SWAP switching B-cell complex 70 antikoerper, SWAP switching B-cell complex 70kDa subunit antikoerper, switching B-cell complex subunit SWAP70a antikoerper, SWAP70 antikoerper, Swap70 antikoerper, swap70 antikoerper, swap70a antikoerper

Hintergrund: Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. SWAP70 also mediates signaling of membrane ruffling. It regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion.
Alias Symbols: FLJ39540, HSPC321, KIAA0640, SWAP-70
Protein Interaction Partner: ZBTB5, RAPGEF4, UBC, CORO1B, ASUN, OTUD6B, JMJD6, GANAB, PACSIN2, FAF1, PAICS, FARSB, ZRANB2, RANBP3, CUL1, SUPT5H, SET, PPP2R5C, PLOD2, OSBP, GART, XRCC6, CRMP1, ATP6V1B2, C18orf8, CELSR3, IGHG1, PARP1, NPM1, NCL,
Protein Size: 585

Molekulargewicht: 69 kDa

Gen-ID: 23075

NCBI Accession: NM_015055, NP_055870

UniProt: Q9UH65

Pathways: Production of Molecular Mediator of Immune Response