MRPS12 Antikörper (N-Term)
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- Target Alle MRPS12 Antikörper anzeigen
- MRPS12 (Mitochondrial Ribosomal Protein S12 (MRPS12))
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Bindungsspezifität
- N-Term
- Reaktivität
- Human, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MRPS12 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- LVPRLWATCS MATLNQMHRL GPPKRPPRKL GPTEGRPQLK GVVLCTFTRK
- Homologie
- Cow: 86%, Dog: 91%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Rat: 86%
- Produktmerkmale
- This is a rabbit polyclonal antibody against MRPS12. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human MRPS12
- Top Product
- Discover our top product MRPS12 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 138 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- MRPS12 (Mitochondrial Ribosomal Protein S12 (MRPS12))
- Andere Bezeichnung
- MRPS12 (MRPS12 Produkte)
- Synonyme
- MPR-S12 antikoerper, MT-RPS12 antikoerper, RPMS12 antikoerper, RPS12 antikoerper, RPSM12 antikoerper, AI327385 antikoerper, Rpms12 antikoerper, rps12 antikoerper, CG7925 antikoerper, Dmel\\CG7925 antikoerper, EG:BACH59J11.1 antikoerper, MRP-S12 antikoerper, MRPS12 antikoerper, S12 antikoerper, Tko antikoerper, l(1)3Ab antikoerper, l(1)tko antikoerper, mRpS12 antikoerper, mt-rps12 antikoerper, MGC64304 antikoerper, GB10531 antikoerper, mitochondrial ribosomal protein S12 antikoerper, technical knockout antikoerper, mitochondrial ribosomal protein S12 L homeolog antikoerper, 40S ribosomal protein S12, mitochondrial antikoerper, putative mitochondrial 37S ribosomal protein MRPS12 antikoerper, fragile site, aphidicolin type, common, fra(6)(p22.2) antikoerper, MRPS12 antikoerper, Mrps12 antikoerper, tko antikoerper, mrps12.L antikoerper, LOC409723 antikoerper, mRpS12 antikoerper, mrps12 antikoerper, CAALFM_C106070WA antikoerper, mrpS12 antikoerper, FRA6C antikoerper
- Hintergrund
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Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. MRPS12 is the 28S subunit protein that belongs to the ribosomal protein S12P family. The protein is a key component of the ribosomal small subunit and controls the decoding fidelity and susceptibility to aminoglycoside antibiotics.Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S12P family. The encoded protein is a key component of the ribosomal small subunit and controls the decoding fidelity and susceptibility to aminoglycoside antibiotics. The gene for mitochondrial seryl-tRNA synthetase is located upstream and adjacent to this gene, and both genes are possible candidates for the autosomal dominant deafness gene (DFNA4). Splice variants that differ in the 5' UTR have been found for this gene, all three variants encode the same protein.
Alias Symbols: MPR-S12, MT-RPS12, RPMS12, RPS12, RPSM12
Protein Interaction Partner: UBC, LRIF1, SPINK7, C14orf1, UNC119, CRMP1,
Protein Size: 138 - Molekulargewicht
- 12 kDa
- Gen-ID
- 6183
- NCBI Accession
- NM_021107, NP_066930
- UniProt
- O15235
- Pathways
- Sensory Perception of Sound
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