CENPM Antikörper (Middle Region)

Produktnummer ABIN2782583

Produktdetails anti-CENPM Antikörper

Target: CENPM (Centromere Protein M (CENPM))

Bindungsspezifität: Middle Region

Reaktivität: Human, Rind (Kuh), Kaninchen, Hund, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CENPM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: CDLEVEGFRA TMAQRLVRVL QICAGHVPGV SALNLLSLLR SSEGPSLEDL

Homologie: Cow: 79%, Dog: 79%, Horse: 93%, Human: 100%, Pig: 93%, Rabbit: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against CENPM. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CENPM

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 180 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CENPM

Target: CENPM (Centromere Protein M (CENPM))

Andere Bezeichnung: CENPM (CENPM Produkte)

Hintergrund: The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA replaces histone H3. CENPM is an additional factor required for centromere assembly.The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPM is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).[supplied by OMIM].
Alias Symbols: C22orf18, CENP-M, MGC861, PANE1, bK250D10.2
Protein Interaction Partner: CENPP, CENPL, CENPT, CENPU, CENPO, CENPK, CENPN, CENPQ, CENPI, CENPC, CENPA, UBC,
Protein Size: 180

Molekulargewicht: 20 kDa

Gen-ID: 79019

NCBI Accession: NM_024053, NP_076958

UniProt: Q9NSP4