CDT1 Antikörper (C-Term)
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- Target Alle CDT1 Antikörper anzeigen
- CDT1 (Chromatin Licensing and DNA Replication Factor 1 (CDT1))
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Bindungsspezifität
- C-Term
- Reaktivität
- Human, Maus, Ratte, Schwein, Rind (Kuh), Hund, Kaninchen, Saccharomyces cerevisiae
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CDT1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- PATPPATPPA ASPSALKGVS QDLLERIRAK EAQKQLAQMT RCPEQEQRLQ
- Homologie
- Cow: 93%, Dog: 77%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Yeast: 85%
- Produktmerkmale
- This is a rabbit polyclonal antibody against CDT1. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human CDT1
- Top Product
- Discover our top product CDT1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 546 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CDT1 (Chromatin Licensing and DNA Replication Factor 1 (CDT1))
- Andere Bezeichnung
- CDT1 (CDT1 Produkte)
- Synonyme
- CDT1 antikoerper, fc37h07 antikoerper, im:7158083 antikoerper, wu:fc37h07 antikoerper, wu:fi38h09 antikoerper, xcdt1 antikoerper, DUP antikoerper, RIS2 antikoerper, 2610318F11Rik antikoerper, AW545653 antikoerper, C76791 antikoerper, Ris2 antikoerper, dup antikoerper, ris2 antikoerper, chromatin licensing and DNA replication factor 1 antikoerper, chromatin licensing and DNA replication factor 1 L homeolog antikoerper, CDT1 antikoerper, cdt1 antikoerper, Cdt1 antikoerper, cdt1.L antikoerper
- Hintergrund
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CDT1 cooperates with CDC6 to promote the loading of the mini-chromosome maintenance complex onto chromatin to form the pre-replication complex necessary to initiate DNA replication. It binds DNA in a sequence-, strand-, and conformation-independent manner and is a potential oncogene.
Alias Symbols: DUP, RIS2
Protein Interaction Partner: FBXO31, SKP1, RBX1, CUL1, DTL, PCNA, HECW2, CDK2, CDC6, CDC5L, ORC2, ORC1, GMNN, DGCR8, UBC, SKP2, CDK1, CCNB1, CCNA2, FOXO3, DDB1, COPS5, CUL4A, CUL4B, SMARCA5, MCM6, MAPK8, MAPK1, HDAC11, KAT7, CCNA1, DDB2, CDK4, CCNE1, TP63, TP73, EP300, KAT2B, CDT1, U
Protein Size: 546 - Molekulargewicht
- 60 kDa
- Gen-ID
- 81620
- NCBI Accession
- NM_030928, NP_112190
- UniProt
- Q9H211
- Pathways
- MAPK Signalweg, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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