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ADAM15 Antikörper (Middle Region)

ADAM15 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein, Kaninchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2782601
  • Target Alle ADAM15 Antikörper anzeigen
    ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))
    Bindungsspezifität
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 34
    • 13
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein, Kaninchen
    Wirt
    • 28
    • 4
    • 2
    • 1
    Kaninchen
    Klonalität
    • 28
    • 5
    Polyklonal
    Konjugat
    • 20
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ADAM15 Antikörper ist unkonjugiert
    Applikation
    • 24
    • 13
    • 12
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    QPAAPLCLQT ANTRGNAFGS CGRNPSGSYV SCTPRDAICG QLQCQTGRTQ
    Homologie
    Cow: 86%, Dog: 79%, Guinea Pig: 79%, Horse: 85%, Human: 100%, Mouse: 100%, Pig: 85%, Rabbit: 79%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against ADAM15. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human ADAM15
    Top Product
    Discover our top product ADAM15 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 862 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))
    Andere Bezeichnung
    ADAM15 (ADAM15 Produkte)
    Synonyme
    ADAM15 antikoerper, mdc15 antikoerper, MDC15 antikoerper, metargidin antikoerper, tMDCVI antikoerper, ADAM metallopeptidase domain 15 antikoerper, ADAM metallopeptidase domain 15 L homeolog antikoerper, a disintegrin and metallopeptidase domain 15 (metargidin) antikoerper, ADAM15 antikoerper, adam15.L antikoerper, adam15 antikoerper, Adam15 antikoerper
    Hintergrund
    ADAM15 is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling.The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
    Alias Symbols: MDC15
    Protein Interaction Partner: BANP, NUP62, RBPMS, UBC, SP4, FHL3, FBXO6, SH3PXD2A, SRC, PTK6, MAPK3, MAPK1, NCK1, GRB2, SNX30, SH3RF3, SNX9, SH3GLB1, PACSIN3, ARHGEF6, ARHGEF7, SORBS2, YES1, NPHP1, LYN, LCK, HCK, FYN, SH3D19, SH3RF1, SORBS3, SNX33, SORBS1, TRIP13, SH3GL2, ABL1, MAD2L1
    Protein Size: 862
    Molekulargewicht
    70 kDa
    Gen-ID
    8751
    NCBI Accession
    NM_207196, NP_997079
    UniProt
    Q71S69
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