FcRn Antikörper (N-Term)

Produktnummer ABIN2782616

Produktdetails anti-FcRn Antikörper

Target: FcRn (IgG receptor FcRn (FcRn))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Schaf, Rind (Kuh), Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FcRn Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: GWLGPQQYLS YNSLRGEAEP CGAWVWENQV SWYWEKETTD LRIKEKLFLE

Homologie: Cow: 79%, Dog: 79%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 79%, Sheep: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against FCGRT. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FCGRT

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 365 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and may contain up to 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FcRn

Target: FcRn (IgG receptor FcRn (FcRn))

Andere Bezeichnung: FCGRT (FcRn Produkte)

Synonyme: FCRN antikoerper, alpha-chain antikoerper, FcRn antikoerper, Fc fragment of IgG receptor and transporter antikoerper, Fc receptor, IgG, alpha chain transporter antikoerper, FCGRT antikoerper, Fcgrt antikoerper

Hintergrund: FCGRT binds to the Fc region of monomeric immunoglobulins gamma. It mediates the uptake of IgG from milk. It plays a possible role in transfer of immunoglobulin G from mother to fetus.
Alias Symbols: FCRN, alpha-chain
Protein Interaction Partner: ATG16L1, FCGRT, CA6, B2M, ALB,
Protein Size: 365

Molekulargewicht: 40 kDa

Gen-ID: 2217

NCBI Accession: NM_004107, NP_004098

UniProt: P55899

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process