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COX15 Antikörper (N-Term)

COX15 Reaktivität: Human, Ratte, Maus, Kaninchen, Hund, Zebrafisch (Danio rerio), Rind (Kuh), Saccharomyces cerevisiae, Meerschweinchen, Pferd IHC, WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2782632
  • Target Alle COX15 Antikörper anzeigen
    COX15 (Cytochrome C Oxidase Assembly Homolog 15 (COX15))
    Bindungsspezifität
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    Human, Ratte, Maus, Kaninchen, Hund, Zebrafisch (Danio rerio), Rind (Kuh), Saccharomyces cerevisiae, Meerschweinchen, Pferd
    Wirt
    • 23
    • 2
    Kaninchen
    Klonalität
    • 24
    • 1
    Polyklonal
    Konjugat
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser COX15 Antikörper ist unkonjugiert
    Applikation
    • 12
    • 11
    • 10
    • 4
    • 3
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB)
    Sequenz
    DWHLIKEMKP PTSQEEWEAE FQRYQQFPEF KILNHDMTLT EFKFIWYMEY
    Homologie
    Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%, Yeast: 82%, Zebrafish: 79%
    Produktmerkmale
    This is a rabbit polyclonal antibody against COX15. It was validated on Western Blot and immunohistochemistry.
    Aufreinigung
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human COX15
    Top Product
    Discover our top product COX15 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 388 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Swenson, Cannon, Harris, Taylor, Fox, Khalimonchuk: "Analysis of Oligomerization Properties of Heme a Synthase Provides Insights into Its Function in Eukaryotes." in: The Journal of biological chemistry, Vol. 291, Issue 19, pp. 10411-25, (2016) (PubMed).

  • Target
    COX15 (Cytochrome C Oxidase Assembly Homolog 15 (COX15))
    Andere Bezeichnung
    COX15 (COX15 Produkte)
    Synonyme
    COX15 antikoerper, wu:fa18g06 antikoerper, zgc:56240 antikoerper, zgc:77422 antikoerper, 2900026G05Rik antikoerper, CEMCOX2 antikoerper, COX15, cytochrome c oxidase assembly homolog antikoerper, COX15 homolog, cytochrome c oxidase assembly protein (yeast) antikoerper, COX15 cytochrome c oxidase assembly homolog antikoerper, cytochrome c oxidase assembly homolog 15 (yeast) antikoerper, cytochrome c oxidase assembly protein 15 antikoerper, cytochrome c oxidase assembly protein COX15 homolog antikoerper, COX15 antikoerper, Cox15 antikoerper, cox15 antikoerper, LOC100410987 antikoerper, LOC100599631 antikoerper
    Hintergrund
    Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be essential for the biogenesis of COX formation and may function in the hydroxylation of heme O, according to the yeast mutant studies. This protein is predicted to contain 5 transmembrane domains localized in the mitochondrial inner membrane.Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be essential for the biogenesis of COX formation and may function in the hydroxylation of heme O, according to the yeast mutant studies. This protein is predicted to contain 5 transmembrane domains localized in the mitochondrial inner membrane. Alternative splicing of this gene generates several transcript variants diverging in the 3' region including alternate poly A sites. In total, 2 different isoforms are encoded by these variants.
    Alias Symbols: -
    Protein Interaction Partner: UBC, CLN3, MRPS14, NDUFA12, TOMM7, MRPL15, LAMTOR3, SURF1, NDUFS8, NDUFS6, NDUFS4, NDUFA9, CYC1,
    Protein Size: 388
    Molekulargewicht
    44 kDa
    Gen-ID
    1355
    NCBI Accession
    NM_004376, NP_004367
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