MMP20 Antikörper (Middle Region)

Produktnummer ABIN2782654

Produktdetails anti-MMP20 Antikörper

Target: MMP20 (Matrix Metalloproteinase 20 (MMP20))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Schwein, Rind (Kuh), Hund, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMP20 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AAVYLREPQK TLFFVGDEYY SYDERKRKME KDYPKNTEEE FSGVNGQIDA

Homologie: Cow: 93%, Dog: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 86%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against MMP20. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MMP20

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 483 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MMP20

Target: MMP20 (Matrix Metalloproteinase 20 (MMP20))

Andere Bezeichnung: MMP20 (MMP20 Produkte)

Synonyme: AI2A2 antikoerper, MMP-20 antikoerper, MMP25 antikoerper, MMP20 antikoerper, mmp20 antikoerper, matrix metallopeptidase 20 antikoerper, matrix metallopeptidase 20 L homeolog antikoerper, matrix metallopeptidase 20 (enamelysin) antikoerper, MMP20 antikoerper, mmp20.L antikoerper, Mmp20 antikoerper

Hintergrund: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP20 degrades amelogenin, the major protein component of dental enamel matrix, and so the protein is thought to play a role in tooth enamel formation. A mutation in the gene encoding MMP20, which alters the normal splice pattern and results in premature termination of the encoded protein, has been associated with amelogenesis imperfecta.
Alias Symbols: AI2A2, MMP-20
Protein Interaction Partner: ACAN,
Protein Size: 483

Molekulargewicht: 43 kDa

Gen-ID: 9313

NCBI Accession: NM_004771, NP_004762

UniProt: O60882