ALDH6A1 Antikörper (Middle Region)

Produktnummer ABIN2782682

Produktdetails anti-ALDH6A1 Antikörper

Target: ALDH6A1 (Aldehyde Dehydrogenase 6 Family, Member A1 (ALDH6A1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Schwein, Kaninchen, Pferd, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALDH6A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: GQVGVNVPIP VPLPMFSFTG SRSSFRGDTN FYGKQGIQFY TQLKTITSQW

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ALDH6A1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ALDH6A1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 535 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ALDH6A1 Antikörper (ABIN2782682)

Kuiper, Williams, Distl, Drögemüller: "Assignment of the PAX6 gene to bovine chromosome 15q25-->q27 by fluorescence in situ hybridization and confirmation by radiation hybrid mapping." in: Cytogenetic and genome research, Vol. 109, Issue 4, pp. 533, (2005) (PubMed).

Details zu ALDH6A1

Target: ALDH6A1 (Aldehyde Dehydrogenase 6 Family, Member A1 (ALDH6A1))

Andere Bezeichnung: ALDH6A1 (ALDH6A1 Produkte)

Synonyme: MMSADHA antikoerper, MMSDH antikoerper, Mmsdh antikoerper, cb850 antikoerper, wu:fb03a04 antikoerper, zgc:92082 antikoerper, 1110038I05Rik antikoerper, AI314632 antikoerper, aldehyde dehydrogenase 6 family member A1 antikoerper, aldehyde dehydrogenase 6 family, member A1 antikoerper, aldehyde dehydrogenase 6 family member A1 L homeolog antikoerper, methylmalonic acid semialdehyde dehydrogenase antikoerper, methylmalonate-semialdehyde dehydrogenase (CoA acylating) antikoerper, aldehyde dehydrogenase family 6, subfamily A1 antikoerper, ALDH6A1 antikoerper, Aldh6a1 antikoerper, aldh6a1.L antikoerper, CCNA_02357 antikoerper, aldh6a1 antikoerper, VAA_RS07845 antikoerper

Hintergrund: ALDH6A1 plays a role in valine and pyrimidine metabolism. ALDH6A1 binds fatty acyl-CoA. This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.
Alias Symbols: MGC40271, MMSADHA, MMSDH
Protein Interaction Partner: UBC, LMO2,
Protein Size: 535

Molekulargewicht: 58 kDa

Gen-ID: 4329

NCBI Accession: NM_005589, NP_005580

UniProt: Q02252

Pathways: Brown Fat Cell Differentiation