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SPTLC1 Antikörper (Middle Region)

SPTLC1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio), Pferd, Hund, Saccharomyces cerevisiae WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2782713
  • Target Alle SPTLC1 Antikörper anzeigen
    SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))
    Bindungsspezifität
    • 15
    • 7
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 59
    • 18
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio), Pferd, Hund, Saccharomyces cerevisiae
    Wirt
    • 59
    • 1
    Kaninchen
    Klonalität
    • 59
    • 1
    Polyklonal
    Konjugat
    • 23
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SPTLC1 Antikörper ist unkonjugiert
    Applikation
    • 47
    • 20
    • 13
    • 13
    • 8
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    ICPLPELVKL KYKYKARIFL EESLSFGVLG EHGRGVTEHY GINIDDIDLI
    Homologie
    Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%, Zebrafish: 93%
    Produktmerkmale
    This is a rabbit polyclonal antibody against SPTLC1. It was validated on Western Blot and immunohistochemistry.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human SPTLC1
    Top Product
    Discover our top product SPTLC1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 473 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))
    Andere Bezeichnung
    SPTLC1 (SPTLC1 Produkte)
    Synonyme
    ATSPT1 antikoerper, SERINE PALMITOYLTRANSFERASE 1 antikoerper, serine palmitoyltransferase 1 antikoerper, Afu6g00300 antikoerper, HSAN1 antikoerper, HSN1 antikoerper, LBC1 antikoerper, LCB1 antikoerper, SPT1 antikoerper, SPTI antikoerper, wu:fc75h04 antikoerper, wu:fp41c08 antikoerper, zgc:112247 antikoerper, AW552086 antikoerper, C77762 antikoerper, E030036H05 antikoerper, Lcb1 antikoerper, RGD1306617 antikoerper, Spt1 antikoerper, serine palmitoyltransferase 1 antikoerper, Serine palmitoyltransferase 1 antikoerper, serine palmitoyltransferase long chain base subunit 1 antikoerper, serine palmitoyltransferase, long chain base subunit 1 antikoerper, serine palmitoyltransferase, long chain base subunit 1 L homeolog antikoerper, SPT1 antikoerper, AFUA_6G00300 antikoerper, PAS_FragB_0040 antikoerper, SPTLC1 antikoerper, sptlc1 antikoerper, sptlc1.L antikoerper, Sptlc1 antikoerper
    Hintergrund
    Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. SPTLC1 is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in SPTLC1 gene were identified in patients with hereditary sensory neuropathy type 1.Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. The product of this gene is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified.
    Alias Symbols: HSAN, HSAN1, HSN1, LBC1, LCB1, MGC14645, SPT1, SPTI, hLCB1
    Protein Interaction Partner: UBC, FBXO6, EGFR, ADRB2, CFTR, ABCA1, UBD, AUP1, MYC, ATG4C, ORMDL3, SPTLC2, C20orf24, MAGED1, RGS20,
    Protein Size: 473
    Molekulargewicht
    53 kDa
    Gen-ID
    10558
    NCBI Accession
    NM_006415, NP_006406
    UniProt
    O15269
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