SPTLC1 Antikörper (Middle Region)
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- Target Alle SPTLC1 Antikörper anzeigen
- SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio), Pferd, Hund, Saccharomyces cerevisiae
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SPTLC1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- ICPLPELVKL KYKYKARIFL EESLSFGVLG EHGRGVTEHY GINIDDIDLI
- Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%, Zebrafish: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against SPTLC1. It was validated on Western Blot and immunohistochemistry.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human SPTLC1
- Top Product
- Discover our top product SPTLC1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 473 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))
- Andere Bezeichnung
- SPTLC1 (SPTLC1 Produkte)
- Synonyme
- ATSPT1 antikoerper, SERINE PALMITOYLTRANSFERASE 1 antikoerper, serine palmitoyltransferase 1 antikoerper, Afu6g00300 antikoerper, HSAN1 antikoerper, HSN1 antikoerper, LBC1 antikoerper, LCB1 antikoerper, SPT1 antikoerper, SPTI antikoerper, wu:fc75h04 antikoerper, wu:fp41c08 antikoerper, zgc:112247 antikoerper, AW552086 antikoerper, C77762 antikoerper, E030036H05 antikoerper, Lcb1 antikoerper, RGD1306617 antikoerper, Spt1 antikoerper, serine palmitoyltransferase 1 antikoerper, Serine palmitoyltransferase 1 antikoerper, serine palmitoyltransferase long chain base subunit 1 antikoerper, serine palmitoyltransferase, long chain base subunit 1 antikoerper, serine palmitoyltransferase, long chain base subunit 1 L homeolog antikoerper, SPT1 antikoerper, AFUA_6G00300 antikoerper, PAS_FragB_0040 antikoerper, SPTLC1 antikoerper, sptlc1 antikoerper, sptlc1.L antikoerper, Sptlc1 antikoerper
- Hintergrund
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Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. SPTLC1 is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in SPTLC1 gene were identified in patients with hereditary sensory neuropathy type 1.Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. The product of this gene is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified.
Alias Symbols: HSAN, HSAN1, HSN1, LBC1, LCB1, MGC14645, SPT1, SPTI, hLCB1
Protein Interaction Partner: UBC, FBXO6, EGFR, ADRB2, CFTR, ABCA1, UBD, AUP1, MYC, ATG4C, ORMDL3, SPTLC2, C20orf24, MAGED1, RGS20,
Protein Size: 473 - Molekulargewicht
- 53 kDa
- Gen-ID
- 10558
- NCBI Accession
- NM_006415, NP_006406
- UniProt
- O15269
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