SEC63 Antikörper (N-Term)

Produktnummer ABIN2782761

Produktdetails anti-SEC63 Antikörper

Target: SEC63 (SEC63 Homolog (SEC63))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen, Rind (Kuh), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SEC63 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: WPRDQNAEQI RLKNIRKVYG RCMWYRLRLL KPQPNIIPTV KKIVLLAGWA

Homologie: Cow: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against SEC63. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SEC63

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 760 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SEC63 Antikörper (ABIN2782761)

You, Li, Kim, Kang, Koh, Chwae, Kim, Kim, Park, Jang, Kim: "Selective translational repression of truncated proteins from frameshift mutation-derived mRNAs in tumors." in: PLoS biology, Vol. 5, Issue 5, pp. e109, (2007) (PubMed).

Details zu SEC63

Target: SEC63 (SEC63 Homolog (SEC63))

Andere Bezeichnung: SEC63 (SEC63 Produkte)

Synonyme: DNAJC23 antikoerper, ERdj2 antikoerper, PRO2507 antikoerper, SEC63L antikoerper, 5730478J10Rik antikoerper, AI649014 antikoerper, AW319215 antikoerper, SEC63-like antikoerper, zgc:92718 antikoerper, SEC63 homolog, protein translocation regulator antikoerper, SEC63-like (S. cerevisiae) antikoerper, SEC63 homolog, protein translocation regulator L homeolog antikoerper, SEC63 antikoerper, Sec63 antikoerper, sec63 antikoerper, sec63.L antikoerper

Hintergrund: The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. SEC63 and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may
Alias Symbols: ERdj2, PRO2507, SEC63L, DNAJC23
Protein Interaction Partner: UBC, IRF1, SEC61B, SEC62, GSTK1,
Protein Size: 760

Molekulargewicht: 88 kDa

Gen-ID: 11231

NCBI Accession: NM_007214, NP_009145

UniProt: Q9UGP8

Pathways: ER-Nucleus Signaling