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BACE2 Antikörper (Middle Region)

BACE2 Reaktivität: Human, Ratte, Maus, Meerschweinchen, Rind (Kuh), Hund, Pferd, Kaninchen, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2782767
  • Target Alle BACE2 Antikörper anzeigen
    BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))
    Bindungsspezifität
    • 15
    • 8
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 43
    • 32
    • 11
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Ratte, Maus, Meerschweinchen, Rind (Kuh), Hund, Pferd, Kaninchen, Zebrafisch (Danio rerio)
    Wirt
    • 62
    • 2
    • 1
    Kaninchen
    Klonalität
    • 64
    • 1
    Polyklonal
    Konjugat
    • 29
    • 10
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BACE2 Antikörper ist unkonjugiert
    Applikation
    • 46
    • 31
    • 20
    • 13
    • 13
    • 12
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    Western Blotting (WB)
    Sequenz
    SLNLDCREYN ADKAIVDSGT TLLRLPQKVF DAVVEAVARA SLIPEFSDGF
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 85%, Rat: 100%, Zebrafish: 92%
    Produktmerkmale
    This is a rabbit polyclonal antibody against BACE2. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human BACE2
    Top Product
    Discover our top product BACE2 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 396 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))
    Andere Bezeichnung
    BACE2 (BACE2 Produkte)
    Synonyme
    AEPLC antikoerper, ALP56 antikoerper, ASP1 antikoerper, ASP21 antikoerper, BAE2 antikoerper, CEAP1 antikoerper, DRAP antikoerper, 1110059C24Rik antikoerper, AI850424 antikoerper, ARP1 antikoerper, CDA13 antikoerper, beta-site APP-cleaving enzyme 2 antikoerper, BACE2 antikoerper, Bace2 antikoerper
    Hintergrund
    Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by this gene. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease. Three transcript variants encoding different isoforms have been described for this gene.
    Alias Symbols: AEPLC, ALP56, ASP1, ASP21, BAE2, CDA13, CEAP1, DRAP
    Protein Interaction Partner: UBC, BACE2, APP, GGA1, GGA2,
    Protein Size: 396
    Molekulargewicht
    37 kDa
    Gen-ID
    25825
    NCBI Accession
    NM_138992, NP_620477
    UniProt
    Q9Y5Z0
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