Myoferlin Antikörper (C-Term)

Produktnummer ABIN2782797

Der Kaninchen Polyklonal Anti-Myoferlin-Antikörper wurde für WB validiert. Er ist geeignet, Myoferlin in Proben von Human, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Ratte und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für Myoferlin Antikörper (C-Term) (ABIN2782797)

Target: Myoferlin (MYOF)

Reaktivität: Human, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Ratte, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Myoferlin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Myoferlin Antikörper

Bindungsspezifität: C-Term

Sequenz: QTEFRIPPRL IIQIWDNDKF SLDDYLGFLE LDLRHTIIPA KSPEKCRLDM

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against FER1L3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FER1L3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 2061 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Myoferlin

Target: Myoferlin (MYOF)

Andere Bezeichnung: FER1L3

Hintergrund: Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. FER1L3 is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length natures have not been determined.
Alias Symbols: FLJ36571, FLJ90777, MYOF, FER1L3
Protein Interaction Partner: UBC, SUMO2, SUMO3, RPA3, RPA2, RPA1, MATR3, ILF2, ATP6V1B1, CDK2, Kdr, Dnm2, ISG15, SUMO1,
Protein Size: 2061

Molekulargewicht: 235 kDa

Gen-ID: 26509

NCBI Accession: NM_013451, NP_038479

UniProt: Q9NZM1