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PCDHA4 Antikörper (C-Term)

PCDHA4 Reaktivität: Human, Meerschweinchen, Ratte, Hund, Pferd, Maus, Rind (Kuh) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2782799
  • Target Alle PCDHA4 Antikörper anzeigen
    PCDHA4 (Protocadherin alpha 4 (PCDHA4))
    Bindungsspezifität
    • 9
    • 8
    • 7
    • 2
    • 2
    • 1
    • 1
    C-Term
    Reaktivität
    • 23
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Meerschweinchen, Ratte, Hund, Pferd, Maus, Rind (Kuh)
    Wirt
    • 21
    • 2
    Kaninchen
    Klonalität
    • 23
    Polyklonal
    Konjugat
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser PCDHA4 Antikörper ist unkonjugiert
    Applikation
    • 22
    • 13
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    SGYNAWLSYE LQPETASASI PFRVGLYTGE ISTTRALDET DAPRQRLLVL
    Homologie
    Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rat: 93%
    Produktmerkmale
    This is a rabbit polyclonal antibody against PCDHA4. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human PCDHA4
    Top Product
    Discover our top product PCDHA4 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 947 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    PCDHA4 (Protocadherin alpha 4 (PCDHA4))
    Andere Bezeichnung
    PCDHA4 (PCDHA4 Produkte)
    Synonyme
    CNR1 antikoerper, CNRN1 antikoerper, CRNR1 antikoerper, PCDH-ALPHA4 antikoerper, Cnr1 antikoerper, Crnr1 antikoerper, R75250 antikoerper, PCDHA4 antikoerper, CNRv4 antikoerper, Pcdha4 antikoerper, protocadherin alpha 4 antikoerper, protocadherin alpha-4 antikoerper, PCDHA4 antikoerper, Pcdha4 antikoerper, LOC100713594 antikoerper, LOC100629843 antikoerper
    Hintergrund
    The gene encoding PCDHA4 is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. PCDHA4 is a single-pass type I membrane protein. It contains 6 cadherin domains. PCDHA4 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
    Alias Symbols: CNR1, CNRN1, CRNR1, MGC138307, MGC142169, PCDH-ALPHA4
    Protein Interaction Partner: SGTA, LRIF1, CCDC90B, RBM48, IGSF21, SETDB1, C14orf1, UNC119, GDF9, RELN, TLE1, TP53, GAPDH, EEF1A1, APLP1,
    Protein Size: 947
    Molekulargewicht
    99 kDa
    Gen-ID
    56144
    NCBI Accession
    NM_018907, NP_061730
    UniProt
    Q9UN74
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