CLN6 Antikörper (C-Term)

Produktnummer ABIN2782927

Produktdetails anti-CLN6 Antikörper

Target: CLN6 (Ceroid-Lipofuscinosis, Neuronal 6, Late Infantile, Variant (CLN6))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Meerschweinchen, Rind (Kuh), Kaninchen, Schaf, Zebrafisch (Danio rerio), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLN6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: RLFLDSNGLF LFSSFALTLL LVALWVAWLW NDPVLRKKYP GVIYVPEPWA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against CLN6. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CLN6

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 311 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CLN6

Target: CLN6 (Ceroid-Lipofuscinosis, Neuronal 6, Late Infantile, Variant (CLN6))

Andere Bezeichnung: CLN6 (CLN6 Produkte)

Synonyme: 1810065L06Rik antikoerper, AW743417 antikoerper, D9Bwg1455e antikoerper, nclf antikoerper, CLN4A antikoerper, HsT18960 antikoerper, cln6 antikoerper, zgc:103565 antikoerper, ceroid-lipofuscinosis, neuronal 6 antikoerper, CLN6, transmembrane ER protein antikoerper, CLN6, transmembrane ER protein S homeolog antikoerper, ceroid-lipofuscinosis, neuronal 6, late infantile, variant antikoerper, CLN6, transmembrane ER protein a antikoerper, Cln6 antikoerper, CLN6 antikoerper, cln6.S antikoerper, cln6a antikoerper

Hintergrund: CLN6 is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely CLN6 involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.
Alias Symbols: FLJ20561, HsT18960, nclf, CLN4A
Protein Interaction Partner: RNF2, BMI1, ILK, env, DERL1, VCP, UBC,
Protein Size: 311

Molekulargewicht: 36 kDa

Gen-ID: 54982

NCBI Accession: NM_017882, NP_060352

UniProt: Q9NWW5

Pathways: Glycosaminoglycan Metabolic Process