ADCY10 Antikörper (N-Term)

Produktnummer ABIN2782970

Produktdetails anti-ADCY10 Antikörper

Target: ADCY10 (Adenylate Cyclase 10 (Soluble) (ADCY10))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Kaninchen, Hund, Rind (Kuh), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADCY10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VGHTVRHEYT VIGQKVNLAA RMMMYYPGIV TCDSVTYNGS NLPAYFFKEL

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SAC. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SAC

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1610 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ADCY10 Antikörper (ABIN2782970)

Corredor, Trakhtenberg, Pita-Thomas, Jin, Hu, Goldberg: "Soluble adenylyl cyclase activity is necessary for retinal ganglion cell survival and axon growth." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 22, pp. 7734-44, (2012) (PubMed).

Details zu ADCY10

Target: ADCY10 (Adenylate Cyclase 10 (Soluble) (ADCY10))

Andere Bezeichnung: SAC (ADCY10 Produkte)

Synonyme: HCA2 antikoerper, RP1-313L4.2 antikoerper, SAC antikoerper, SACI antikoerper, Sacy antikoerper, Sac antikoerper, 4930431D04Rik antikoerper, 4931412F17 antikoerper, sAC antikoerper, ADCY10 antikoerper, SACY antikoerper, adenylate cyclase 10 antikoerper, adenylate cyclase 10 (soluble) antikoerper, ADCY10 antikoerper, Adcy10 antikoerper

Hintergrund: SAC belongs to a distinct class of mammalian adenylyl cyclase that is soluble and insensitive to G protein or forskolin regulation. It is localized in the cytoplasm and is thought to function as a general bicarbonate sensor throughout the body. It may also play an important role in the generation of cAMP in spermatozoa, implying possible roles in sperm maturation through the epididymis, capacitation, hypermotility, and/or the acrosome reaction.The protein encoded by this gene belongs to a distinct class of mammalian adenylyl cyclase that is soluble and insensitive to G protein or forskolin regulation. It is localized in the cytoplasm and is thought to function as a general bicarbonate sensor throughout the body. It may also play an important role in the generation of cAMP in spermatozoa, implying possible roles in sperm maturation through the epididymis, capacitation, hypermotility, and/or the acrosome reaction. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HCA2, RP1-313L4.2, SACI, SAC, Sacy
Protein Interaction Partner: PTGIR, SSTR5,
Protein Size: 1610

Molekulargewicht: 187 kDa

Gen-ID: 55811

NCBI Accession: NM_018417, NP_060887

UniProt: Q96PN6

Pathways: cAMP Metabolic Process