FTO Antikörper (Middle Region)
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- Target Alle FTO Antikörper anzeigen
- FTO (Fat Mass and Obesity-Associated (FTO))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Hund, Kaninchen, Pferd, Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FTO Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- WWCQPMAQLE ALWKKMEGVT NAVLHEVKRE GLPVEQRNEI LTAILASLTA
- Homologie
- Dog: 86%, Guinea Pig: 100%, Horse: 79%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against FTO. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human FTO
- Top Product
- Discover our top product FTO Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 505 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- FTO (Fat Mass and Obesity-Associated (FTO))
- Andere Bezeichnung
- FTO (FTO Produkte)
- Synonyme
- AW743446 antikoerper, mKIAA1752 antikoerper, RGD1305121 antikoerper, FTO, alpha-ketoglutarate dependent dioxygenase antikoerper, fat mass and obesity associated antikoerper, fat mass and obesity associated L homeolog antikoerper, FTO antikoerper, Fto antikoerper, fto.L antikoerper
- Hintergrund
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The exact function of this gene is not know. Studies in mice suggest that it may be involved in nucleic acid demethylation, and that its mRNA level is regulated by feeding and fasting. Genomewide association studies of type 2 diabetes indicate this gene as a diabetes susceptibility locus. Mutation in this gene has been associated with growth retardation, developmental delay, coarse facies, and early death.
Alias Symbols: KIAA1752, MGC5149
Protein Interaction Partner: UBC, SUMO1, NEDD8, BCCIP, CNDP2, DAK, NDRG1, NPEPPS, SLC9A3R1, CTSA, PEPD, MVD, LDHB, LDHA, EEF2, CKB,
Protein Size: 505 - Molekulargewicht
- 58 kDa
- Gen-ID
- 79068
- NCBI Accession
- NM_001080432, NP_001073901
- UniProt
- Q9C0B1
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