SMC3 Antikörper (N-Term)

Produktnummer ABIN2783036

Produktdetails anti-SMC3 Antikörper

Target: SMC3 (Structural Maintenance of Chromosomes 3 (SMC3))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Pferd, Zebrafisch (Danio rerio), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KWDKMRRALE YTIYNQELNE TRAKLDELSA KRETSGEKSR QLRDAQQDAR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against SMC3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SMC3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1217 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SMC3

Target: SMC3 (Structural Maintenance of Chromosomes 3 (SMC3))

Andere Bezeichnung: SMC3 (SMC3 Produkte)

Synonyme: cspg6 antikoerper, xsmc3 antikoerper, BAM antikoerper, BMH antikoerper, CDLS3 antikoerper, CSPG6 antikoerper, HCAP antikoerper, SMC3L1 antikoerper, Bamacan antikoerper, Cspg6 antikoerper, Mmip1 antikoerper, SMC-3 antikoerper, SmcD antikoerper, im:7142991 antikoerper, wu:fb22e01 antikoerper, wu:fc30d07 antikoerper, bamacan antikoerper, structural maintenance of chromosomes 3 antikoerper, structural maintenance of chromosomes 3 S homeolog antikoerper, smc3 antikoerper, SMC3 antikoerper, Smc3 antikoerper, smc3.S antikoerper

Hintergrund: SMC3 belongs to the SMC3 subfamily of SMC proteins. SMC3 occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation.
Alias Symbols: BAM, BMH, CDLS3, CSPG6, HCAP, SMC3L1
Protein Interaction Partner: SUMO2, UBC, RPA3, RPA2, RPA1, SUZ12, EED, RNF2, FBXO6, ANKRD28, HDAC11, HDAC8, HDAC9, SOX2, RAD21, CDCA5, PDS5A, WAPAL, MMS19, METTL21B, NOTCH1, SMC1A, SFPQ, HNRNPM, NSMCE2, UBD, COPS5, COPS6, CUL2, CUL3, NEDD8, CDK2, FBXO25, MECP2, NIPBL, CDK8, SUPT5H, P
Protein Size: 1217

Molekulargewicht: 141 kDa

Gen-ID: 9126

NCBI Accession: NM_005445, NP_005436

UniProt: Q9UQE7

Pathways: Stem Cell Maintenance