SETD2 Antikörper (N-Term)

Produktnummer ABIN2783051

Produktdetails anti-SETD2 Antikörper

Target: SETD2 (SET Domain Containing 2 (SETD2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SETD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: SDEDSVRTSS SQRSHDLKFS ASIEKERDFK KSSAPLKSED LGKPSRSKTD

Kreuzreaktivität: Hund, Human, Ratte (Rattus)

Homologie: Cow: 79%, Dog: 86%, Horse: 86%, Human: 100%, Mouse: 83%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against SETD2. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SETD2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 891 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SETD2 Antikörper (ABIN2783051)

Barrand, Andersen, Collas: "Promoter-exon relationship of H3 lysine 9, 27, 36 and 79 methylation on pluripotency-associated genes." in: Biochemical and biophysical research communications, Vol. 401, Issue 4, pp. 611-7, (2010) (PubMed).

Details zu SETD2

Target: SETD2 (SET Domain Containing 2 (SETD2))

Andere Bezeichnung: SETD2 / HIF1 (SETD2 Produkte)

Synonyme: Kif9 antikoerper, HBP231 antikoerper, HIF-1 antikoerper, HIP-1 antikoerper, HYPB antikoerper, KMT3A antikoerper, SET2 antikoerper, p231HBP antikoerper, SET domain containing 2 antikoerper, Setd2 antikoerper, SETD2 antikoerper

Hintergrund: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. SETD2 is a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs.
Alias Symbols: FLJ16420, FLJ22472, FLJ23184, FLJ45883, HIF-1, HSPC069, HYPB, KIAA1732, KMT3A, SET2, HIP-1, HBP231, p231HBP
Protein Interaction Partner: CLK2, SOX2, CBX8, HCVgp1, SIAH2, SMAD3, CIC, ATXN1, ELAVL1, UBC, SETD2, HIST1H3A, POLR2A, TP53, IWS1, HTT,
Protein Size: 891

Molekulargewicht: 97 kDa

Gen-ID: 29072

NCBI Accession: NM_014159

UniProt: Q9BYW2

Pathways: Tube Formation