MAFA Antikörper (N-Term)

Produktnummer ABIN2783127

Produktdetails anti-MAFA Antikörper

Target: MAFA (Transcription Factor MafA (MAFA))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Meerschweinchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAFA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KPALEDLYWM SGYQHHLNPE ALNLTPEDAV EALIGSGHHG AHHGAHHPAA

Kreuzreaktivität: Cow: 100%, Dog: 79%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 83%

Homologie: Cow: 100%, Dog: 79%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against MAFA. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MAFA

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 353 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MAFA

Target: MAFA (Transcription Factor MafA (MAFA))

Andere Bezeichnung: MAFA (MAFA Produkte)

Synonyme: RIPE3b1 antikoerper, hMafA antikoerper, RGD1562627 antikoerper, 2F1-Ag antikoerper, MAFA antikoerper, MAFA-L antikoerper, SMaf1 antikoerper, mafl antikoerper, L-MAF antikoerper, MAFL antikoerper, Maf antikoerper, v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian) antikoerper, MAF bZIP transcription factor A antikoerper, killer cell lectin-like receptor subfamily G, member 1 antikoerper, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A antikoerper, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Aa antikoerper, monocyte to macrophage differentiation-associated antikoerper, Mafa antikoerper, MAFA antikoerper, Klrg1 antikoerper, mafa antikoerper, mafaa antikoerper, Mmd antikoerper

Hintergrund: MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene (INS).MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene (INS, MIM 176730) (Olbrot et al., 2002 [PubMed 12011435]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1062 AC105118.23 99326-100387 c
Alias Symbols: RIPE3b1, hMafA
Protein Interaction Partner: Mapk14, UBC, SUMO1, NEUROD1, PDX1, MAF, MAPK1,
Protein Size: 353

Molekulargewicht: 37 kDa

Gen-ID: 389692

NCBI Accession: NM_201589, NP_963883

UniProt: Q8NHW3

Pathways: Hormone Transport