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EIF4A1 Antikörper (Middle Region)

EIF4A1 Reaktivität: Human, Ratte, Maus, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Schaf, Saccharomyces cerevisiae WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2783213
  • Target Alle EIF4A1 Antikörper anzeigen
    EIF4A1 (Eukaryotic Translation Initiation Factor 4A1 (EIF4A1))
    Bindungsspezifität
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 30
    • 18
    • 17
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Human, Ratte, Maus, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Schaf, Saccharomyces cerevisiae
    Wirt
    • 27
    • 3
    Kaninchen
    Klonalität
    • 26
    • 4
    Polyklonal
    Konjugat
    • 23
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser EIF4A1 Antikörper ist unkonjugiert
    Applikation
    • 23
    • 9
    • 8
    • 7
    • 6
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    TMPSDVLEVT KKFMRDPIRI LVKKEELTLE GIRQFYINVE REEWKLDTLC
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Yeast: 92%, Zebrafish: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against EIF4A1. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human EIF4A1
    Top Product
    Discover our top product EIF4A1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 406 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Tamarkin-Ben-Harush, Vasseur, Debart, Ulitsky, Dikstein: "Cap-proximal nucleotides via differential eIF4E binding and alternative promoter usage mediate translational response to energy stress." in: eLife, Vol. 6, (2017) (PubMed).

  • Target
    EIF4A1 (Eukaryotic Translation Initiation Factor 4A1 (EIF4A1))
    Andere Bezeichnung
    EIF4A1 (EIF4A1 Produkte)
    Synonyme
    DDX2A antikoerper, EIF-4A antikoerper, EIF4A antikoerper, eIF-4A-I antikoerper, eIF4A-I antikoerper, BM-010 antikoerper, Ddx2a antikoerper, Eif4 antikoerper, ddx2a antikoerper, eif-4a antikoerper, eif4a antikoerper, eif4a1 antikoerper, fb49a04 antikoerper, im:7143023 antikoerper, wu:fb20a10 antikoerper, wu:fb49a04 antikoerper, wu:fc76a02 antikoerper, wu:fc96c01 antikoerper, wu:fd15g03 antikoerper, eukaryotic translation initiation factor 4A1 antikoerper, eukaryotic translation initiation factor 4A1 L homeolog antikoerper, eukaryotic initiation factor 4A-I antikoerper, eukaryotic translation initiation factor 4A1A antikoerper, EIF4A1 antikoerper, Eif4a1 antikoerper, eif4a1.L antikoerper, eif4a1 antikoerper, LOC695050 antikoerper, eif4a1a antikoerper
    Hintergrund
    EIF4A1 is an ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
    Alias Symbols: DDX2A, EIF-4A, EIF4A, eIF4A-I, eIF-4A-I
    Protein Interaction Partner: HUWE1, UBC, FUS, SUMO2, SUMO3, STAU1, MDM2, SH3RF2, TRAP1, FBXO6, ADRB2, CD81, NPM1, VCAM1, ITGA4, FN1, ESR1, LIG4, RPLP0P6, TMEM43, NDUFB11, ZBTB43, GPRC5A, EIF4G3, EIF4H, VDAC3, UQCRFS1, SDHA, RPS26, RPL19, RPL8, RPSA, ILF2, HSP90AB1, HSPA5, EIF4G2, EIF
    Protein Size: 406
    Molekulargewicht
    46 kDa
    Gen-ID
    1973
    NCBI Accession
    NM_001416, NP_001407
    UniProt
    P60842
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