Myosin 9 Antikörper (Middle Region)

Produktnummer ABIN2783216

Produktdetails anti-Myosin 9 Antikörper

Target: Myosin 9 (MYH9)

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Schwein, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Myosin 9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: DAMNREVSSL KNKLRRGDLP FVVPRRMARK GAGDGSDEEV DGKADGAEAK

Homologie: Dog: 93%, Guinea Pig: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 86%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against MYH9. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MYH9

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1960 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Myosin 9 Antikörper (ABIN2783216)

Sabbir, Dillon, Mowat: "Dlc1 interaction with non-muscle myosin heavy chain II-A (Myh9) and Rac1 activation." in: Biology open, Vol. 5, Issue 4, pp. 452-60, (2016) (PubMed).

Details zu Myosin 9

Target: Myosin 9 (MYH9)

Andere Bezeichnung: MYH9 (MYH9 Produkte)

Synonyme: BDPLT6 antikoerper, DFNA17 antikoerper, EPSTS antikoerper, FTNS antikoerper, MHA antikoerper, NMHC-II-A antikoerper, NMMHC-IIA antikoerper, NMMHCA antikoerper, C80049 antikoerper, D0Jmb2 antikoerper, E030044M24Rik antikoerper, Fltn antikoerper, Myhn-1 antikoerper, Myhn1 antikoerper, NMHC II-A antikoerper, NMHCIIA antikoerper, NMMHC II-a antikoerper, NMMHC-A antikoerper, TU72.6 antikoerper, fi22c04 antikoerper, myh9 antikoerper, myh9l2 antikoerper, wu:fi22c04 antikoerper, wu:fj85e11 antikoerper, zgc:162029 antikoerper, zgc:66164 antikoerper, NMMHC antikoerper, myosin antikoerper, non-muscle antikoerper, nonmuscle antikoerper, KLG/PTK7 antikoerper, dfna17 antikoerper, epsts antikoerper, ftns antikoerper, nmhc-ii-a antikoerper, nmmhca antikoerper, myosin heavy chain 9 antikoerper, myosin, heavy polypeptide 9, non-muscle antikoerper, myosin, heavy chain 9a, non-muscle antikoerper, myosin, heavy chain 9, non-muscle antikoerper, myosin, heavy chain 9, non-muscle L homeolog antikoerper, MYH9 antikoerper, Myh9 antikoerper, myh9a antikoerper, myh9.L antikoerper

Hintergrund: MYH9 is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain. The protein is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in MYH9 are the cause of non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness.
Alias Symbols: DFNA17, EPSTS, FTNS, MGC104539, MHA, NMHC-II-A, NMMHCA, BDPLT6, NMMHC-IIA
Protein Interaction Partner: HUWE1, UBC, TP53, SUMO2, SUMO3, IVNS1ABP, LGR4, MDM2, RPA3, RPA2, RPA1, EED, MYL6, MYH14, CDC73, OTUD6B, AKAP10, MYL12A, MYL9, TARDBP, FN1, UBD, PIK3C3, ACE, CSNK2A1, ACTB, PAN2, ITGA4, HSP90AB1, HSP90AA1, ESR1, CASP4, IQCB1, VCAM1, PPP2CA, Fcho2, TRAF3IP
Protein Size: 1960

Molekulargewicht: 226 kDa

Gen-ID: 4627

NCBI Accession: NM_002473, NP_002464

UniProt: P35579

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Integrin Complex