TPI1 Antikörper (N-Term)

Produktnummer ABIN2783242

Produktdetails anti-TPI1 Antikörper

Target: TPI1 (Triosephosphate Isomerase 1 (TPI1))

Bindungsspezifität: N-Term

Reaktivität: Human, Kaninchen, Hund, Rind (Kuh), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TPI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MAPSRKFFVG GNWKMNGRKQ SLGELIGTLN AAKVPADTEV VCAPPTAYID

Homologie: Cow: 79%, Dog: 79%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Rabbit: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against TPI1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TPI1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 249 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-TPI1 Antikörper (ABIN2783242)

Ralser, Nebel, Kleindorp, Krobitsch, Lehrach, Schreiber, Reinhardt, Timmermann: "Sequencing and genotypic analysis of the triosephosphate isomerase (TPI1) locus in a large sample of long-lived Germans." in: BMC genetics, Vol. 9, pp. 38, (2008) (PubMed).

Details zu TPI1

Target: TPI1 (Triosephosphate Isomerase 1 (TPI1))

Andere Bezeichnung: TPI1 (TPI1 Produkte)

Hintergrund: TPI1 belongs to the triosephosphate isomerase family. Defects in TPI1 are the cause of triosephosphate isomerase deficiency (TPI deficiency) . TPI deficiency is an autosomal recessive disorder. It is the most severe clinical disorder of glycolysis. It is associated with neonatal jaundice, chronic hemolytic anemia, progressive neuromuscular dysfunction, cardiomyopathy and increased susceptibility to infection.
Alias Symbols: MGC88108, TPI, TIM
Protein Interaction Partner: MDM2, UBC, RNF2, EZH2, SUZ12, TARDBP, YWHAQ, SP1, UBD, HCVgp1, IQCB1, ATF2, LIG4, SSU72, SEC23IP, PDIA6, PRDX6, VCL, UBA52, TKT, PGK1, MPST, GPI, GAPDH, ENO1, APP, CUL1, CDK2, TERF1, POT1, PSMA3, MAPK6, PCNA, HDAC5, UCHL5, EGFR, LIPT1, SETDB1, DDX24, CFL1
Protein Size: 249

Molekulargewicht: 27 kDa

Gen-ID: 7167

NCBI Accession: NM_000365, NP_000356

UniProt: P60174

Pathways: Cell RedoxHomeostasis