AKR1B1 Antikörper (N-Term)

Produktnummer ABIN2783262

Produktdetails anti-AKR1B1 Antikörper

Target: AKR1B1 (Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Hund, Kaninchen, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Rind (Kuh), Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AKR1B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: ASRLLLNNGA KMPILGLGTW KSPPGQVTEA VKVAIDVGYR HIDCAHVYQN

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Yeast: 86%, Zebrafish: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against AKR1B1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human AKR1B1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 316 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu AKR1B1

Target: AKR1B1 (Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1))

Andere Bezeichnung: AKR1B1 (AKR1B1 Produkte)

Synonyme: ADR antikoerper, ALDR1 antikoerper, ALR2 antikoerper, AR antikoerper, ALDRED antikoerper, ALR-P-I antikoerper, Akr1b3 antikoerper, Akr1b4 antikoerper, Aldr1 antikoerper, Alr antikoerper, RATALDRED antikoerper, akr1b7 antikoerper, zgc:86611 antikoerper, aldo-keto reductase family 1 member B antikoerper, aldo-keto reductase family 1, member B1 (aldose reductase) antikoerper, aldo-keto reductase family 1, member B1 (aldose reductase) S homeolog antikoerper, AKR1B1 antikoerper, Akr1b1 antikoerper, akr1b1.S antikoerper, akr1b1 antikoerper

Hintergrund: AKR1B1 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. There are a few putative pseudogenes for this gene, and one of them has been confirmed and mapped to chromosome 3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ADR, ALDR1, ALR2, AR, MGC1804
Protein Interaction Partner: UBC, ASB18, ASB9, ASB5, SMAD1, SORD, SHBG, TFE3,
Protein Size: 316

Molekulargewicht: 36 kDa

Gen-ID: 231

NCBI Accession: NM_001628, NP_001619

UniProt: P15121

Pathways: Metabolism of Steroid Hormones and Vitamin D, C21-Steroid Hormone Metabolic Process, Monocarboxylic Acid Catabolic Process