ARF1 Antikörper (Middle Region)

Produktnummer ABIN2783267

Produktdetails anti-ARF1 Antikörper

Target: ARF1 (ADP-Ribosylation Factor 1 (ARF1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Schaf, Pferd, Zebrafisch (Danio rerio), Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Sequenz: MRMLAEDELR DAVLLVFANK QDLPNAMNAA EITDKLGLHS LRHRNWYIQA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ARF1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ARF1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 181 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ARF1

Target: ARF1 (ADP-Ribosylation Factor 1 (ARF1))

Andere Bezeichnung: ARF1 (ARF1 Produkte)

Synonyme: wu:fb33e02 antikoerper, wu:fb78h01 antikoerper, arf2 antikoerper, arf-1 antikoerper, MGC52573 antikoerper, ADP-RIBOSYLATION FACTOR antikoerper, ADP-RIBOSYLATION FACTOR 1A antikoerper, ADP-ribosylation factor 1 antikoerper, ATARF antikoerper, ATARF1 antikoerper, ATARFA1A antikoerper, F28C11.12 antikoerper, ARF1 antikoerper, arf1 antikoerper, ADP ribosylation factor 1 antikoerper, ADP-ribosylation factor 1 antikoerper, ADP ribosylation factor 1 L homeolog antikoerper, ADP ribosylation factor 5 L homeolog antikoerper, ADP ribosylation factor 1 pseudogene antikoerper, adp-ribosylation factor 1 antikoerper, ARF1 antikoerper, Arf1 antikoerper, arf1 antikoerper, arf1.L antikoerper, arf5.L antikoerper, NCU08340 antikoerper, TRIADDRAFT_63238 antikoerper, PAAG_08805 antikoerper, LOC100280562 antikoerper, LOC100280918 antikoerper, LOC474591 antikoerper, CLUG_01013 antikoerper

Hintergrund: ADP-ribosylation factor 1 (ARF1) is a member of the human ARF family. The family is composed of small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking as activators of phospholipase D. These protein, including 6 ARF proteins and 11 ARF-like proteins, constitute a family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2 and ARF3), class II (ARF4 and ARF5) and class III (ARF6), and members of each class share a common gene organization. The ARF1 protein is localized to the Golgi apparatus and has a central role in intra-Golgi transport. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.ADP-ribosylation factor 1 (ARF1) is a member of the human ARF gene family. The family members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking as activators of phospholipase D. The gene products, including 6 ARF proteins and 11 ARF-like proteins, constitute a family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2 and ARF3), class II (ARF4 and ARF5) and class III (ARF6), and members of each class share a common gene organization. The ARF1 protein is localized to the Golgi apparatus and has a central role in intra-Golgi transport. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
Alias Symbols: -
Protein Interaction Partner: GGA1, GGA3, GGA2, HUWE1, UBC, FBXO6, MMS19, TMEM106A, VCAM1, ITGA4, ATF2, ARF3, UBD, GRK5, CDK2, HERC1, Proser1, AI837181, Kif1c, Bach1, nef, COPB1, GEA1, WBP11, TMED2, PICK1, NOA1, TMED10, EEF1G, PLEKHA8, COPG1, ARFIP1, ARFIP2, ARHGAP21, ARFGAP1, AP3D1,
Protein Size: 181

Molekulargewicht: 21 kDa

Gen-ID: 375

NCBI Accession: NM_001658, NP_001649

UniProt: P61204

Pathways: Transition Metal Ion Homeostasis, Inositol Metabolic Process