CAMLG Antikörper (N-Term)
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- Target Alle CAMLG Antikörper anzeigen
- CAMLG (Calcium Modulating Ligand (CAMLG))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein, Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CAMLG Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- LLMNSEQRIN RIMGFHRPGS GAEEESQTKS KQQDSDKLNS LSVPSVSKRV
- Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 85%
- Produktmerkmale
- This is a rabbit polyclonal antibody against CAMLG. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human CAMLG
- Top Product
- Discover our top product CAMLG Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 296 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CAMLG (Calcium Modulating Ligand (CAMLG))
- Andere Bezeichnung
- CAMLG (CAMLG Produkte)
- Synonyme
- MGC53900 antikoerper, CAML antikoerper, AI385748 antikoerper, Camlg antikoerper, Caml antikoerper, calcium modulating ligand L homeolog antikoerper, calcium modulating ligand antikoerper, camlg.L antikoerper, CAMLG antikoerper, camlg antikoerper, Caml antikoerper, Camlg antikoerper
- Hintergrund
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The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. CAMLG functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.
Alias Symbols: CAML, MGC163197
Protein Interaction Partner: KCNA2, TMUB1, TNFRSF13B, UBC, RNF122, PKHD1, EGFR, PPIB, IER3,
Protein Size: 296 - Molekulargewicht
- 33 kDa
- Gen-ID
- 819
- NCBI Accession
- NM_001745, NP_001736
- UniProt
- P49069
- Pathways
- EGFR Signaling Pathway
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